Yang Z - Search Results

1

LGR4 is a receptor for RANKL and negatively regulates osteoclast differentiation and bone resorption.

Luo J, Yang Z, Ma Y, Yue Z, Lin H, Qu G, Huang J, Dai W, Li C, Zheng C, Xu L, Chen H, Wang J, Li D, Siwko S, Penninger JM, Ning G, Xiao J, Liu M. Luo J, et al. Among authors: yang z. Nat Med. 2016 May;22(5):539-46. doi: 10.1038/nm.4076. Epub 2016 Apr 11. Nat Med. 2016. PMID: 27064449

2

Bortezomib Inhibits Giant Cell Tumor of Bone through Induction of Cell Apoptosis and Inhibition of Osteoclast Recruitment, Giant Cell Formation, and Bone Resorption.

Xu L, Luo J, Jin R, Yue Z, Sun P, Yang Z, Yang X, Wan W, Zhang J, Li S, Liu M, Xiao J. Xu L, et al. Among authors: yang x, yang z. Mol Cancer Ther. 2016 May;15(5):854-65. doi: 10.1158/1535-7163.MCT-15-0669. Epub 2016 Feb 9. Mol Cancer Ther. 2016. PMID: 26861247

3

RSPO2 and RANKL signal through LGR4 to regulate osteoclastic premetastatic niche formation and bone metastasis.

Yue Z, Niu X, Yuan Z, Qin Q, Jiang W, He L, Gao J, Ding Y, Liu Y, Xu Z, Li Z, Yang Z, Li R, Xue X, Gao Y, Yue F, Zhang XH, Hu G, Wang Y, Li Y, Chen G, Siwko S, Gartland A, Wang N, Xiao J, Liu M, Luo J. Yue Z, et al. Among authors: yang z. J Clin Invest. 2022 Jan 18;132(2):e144579. doi: 10.1172/JCI144579. J Clin Invest. 2022. PMID: 34847079 Free PMC article.

4

Maslinic acid suppresses osteoclastogenesis and prevents ovariectomy-induced bone loss by regulating RANKL-mediated NF-κB and MAPK signaling pathways.

Li C, Yang Z, Li Z, Ma Y, Zhang L, Zheng C, Qiu W, Wu X, Wang X, Li H, Tang J, Qian M, Li D, Wang P, Luo J, Liu M. Li C, et al. Among authors: yang z. J Bone Miner Res. 2011 Mar;26(3):644-56. doi: 10.1002/jbmr.242. J Bone Miner Res. 2011. PMID: 20814972 Free article.

5

LGR4 modulates breast cancer initiation, metastasis, and cancer stem cells.

Yue Z, Yuan Z, Zeng L, Wang Y, Lai L, Li J, Sun P, Xue X, Qi J, Yang Z, Zheng Y, Fang Y, Li D, Siwko S, Li Y, Luo J, Liu M. Yue Z, et al. Among authors: yang z. FASEB J. 2018 May;32(5):2422-2437. doi: 10.1096/fj.201700897R. Epub 2017 Dec 21. FASEB J. 2018. PMID: 29269400 Free PMC article.

Our findings support a crucial role of the Wnt signaling component LGR4 in breast cancer initiation, metastasis, and breast CSCs.-Yue, Z., Yuan, Z., Zeng, L., Wang, Y., Lai, L., Li, J., Sun, P., Xue, X., Qi, J., Yang, Z., Zheng, Y., Fang, Y., Li, D., S …

Our findings support a crucial role of the Wnt signaling component LGR4 in breast cancer initiation, metastasis, and breast CSCs.-Yue, Z …

6

Crystal structure of LGR4-Rspo1 complex: insights into the divergent mechanisms of ligand recognition by leucine-rich repeat G-protein-coupled receptors (LGRs).

Xu JG, Huang C, Yang Z, Jin M, Fu P, Zhang N, Luo J, Li D, Liu M, Zhou Y, Zhu Y. Xu JG, et al. Among authors: yang z. J Biol Chem. 2015 Jan 23;290(4):2455-65. doi: 10.1074/jbc.M114.599134. Epub 2014 Dec 5. J Biol Chem. 2015. PMID: 25480784 Free PMC article.

7

Maslinic acid potentiates the anti-tumor activity of tumor necrosis factor alpha by inhibiting NF-kappaB signaling pathway.

Li C, Yang Z, Zhai C, Qiu W, Li D, Yi Z, Wang L, Tang J, Qian M, Luo J, Liu M. Li C, et al. Among authors: yang z. Mol Cancer. 2010 Apr 6;9:73. doi: 10.1186/1476-4598-9-73. Mol Cancer. 2010. PMID: 20367887 Free PMC article.

8

Dauricine induces apoptosis, inhibits proliferation and invasion through inhibiting NF-kappaB signaling pathway in colon cancer cells.

Yang Z, Li C, Wang X, Zhai C, Yi Z, Wang L, Liu B, Du B, Wu H, Guo X, Liu M, Li D, Luo J. Yang Z, et al. J Cell Physiol. 2010 Oct;225(1):266-75. doi: 10.1002/jcp.22261. J Cell Physiol. 2010. PMID: 20509140

9

Inhibition of breast cancer metastases by a novel inhibitor of TGFβ receptor 1.

Fang Y, Chen Y, Yu L, Zheng C, Qi Y, Li Z, Yang Z, Zhang Y, Shi T, Luo J, Liu M. Fang Y, et al. Among authors: yang z. J Natl Cancer Inst. 2013 Jan 2;105(1):47-58. doi: 10.1093/jnci/djs485. Epub 2012 Nov 24. J Natl Cancer Inst. 2013. PMID: 23178439

10

Calcium Homeostasis: A Potential Vicious Cycle of Bone Metastasis in Breast Cancers.

Yang Z, Yue Z, Ma X, Xu Z. Yang Z, et al. Front Oncol. 2020 Mar 10;10:293. doi: 10.3389/fonc.2020.00293. eCollection 2020. Front Oncol. 2020. PMID: 32211326 Free PMC article. Review.

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