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Aspirin prevents colorectal cancer metastasis in mice by splitting the crosstalk between platelets and tumor cells.
Guillem-Llobat P, Dovizio M, Bruno A, Ricciotti E, Cufino V, Sacco A, Grande R, Alberti S, Arena V, Cirillo M, Patrono C, FitzGerald GA, Steinhilber D, Sgambato A, Patrignani P. Guillem-Llobat P, et al. Among authors: grande r. Oncotarget. 2016 May 31;7(22):32462-77. doi: 10.18632/oncotarget.8655. Oncotarget. 2016. PMID: 27074574 Free PMC article.
Platelets in cancer development and diagnosis.
Contursi A, Grande R, Dovizio M, Bruno A, Fullone R, Patrignani P. Contursi A, et al. Among authors: grande r. Biochem Soc Trans. 2018 Dec 17;46(6):1517-1527. doi: 10.1042/BST20180159. Epub 2018 Nov 12. Biochem Soc Trans. 2018. PMID: 30420412 Review.
Platelet-Derived Microparticles From Obese Individuals: Characterization of Number, Size, Proteomics, and Crosstalk With Cancer and Endothelial Cells.
Grande R, Dovizio M, Marcone S, Szklanna PB, Bruno A, Ebhardt HA, Cassidy H, Ní Áinle F, Caprodossi A, Lanuti P, Marchisio M, Mingrone G, Maguire PB, Patrignani P. Grande R, et al. Front Pharmacol. 2019 Jan 22;10:7. doi: 10.3389/fphar.2019.00007. eCollection 2019. Front Pharmacol. 2019. PMID: 30723407 Free PMC article.
Platelets induce free and phospholipid-esterified 12-hydroxyeicosatetraenoic acid generation in colon cancer cells by delivering 12-lipoxygenase.
Contursi A, Schiavone S, Dovizio M, Hinz C, Fullone R, Tacconelli S, Tyrrell VJ, Grande R, Lanuti P, Marchisio M, Zucchelli M, Ballerini P, Lanas A, O'Donnell VB, Patrignani P. Contursi A, et al. Among authors: grande r. J Lipid Res. 2021;62:100109. doi: 10.1016/j.jlr.2021.100109. Epub 2021 Aug 21. J Lipid Res. 2021. PMID: 34428433 Free PMC article.
Therapeutic targeting of dysregulated cellular communication.
Schiavone S, Contursi A, Grande R, Patrignani P. Schiavone S, et al. Among authors: grande r. Ann Transl Med. 2017 May;5(10):222. doi: 10.21037/atm.2017.03.62. Ann Transl Med. 2017. PMID: 28603737 Free PMC article. No abstract available.
403 results