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The T4bSS of Legionella features a two-step secretion pathway with an inner membrane intermediate for secretion of transmembrane effectors.
Malmsheimer S, Grin I, Bohn E, Franz-Wachtel M, Macek B, Sahr T, Smollich F, Chetrit D, Meir A, Roy C, Buchrieser C, Wagner S. Malmsheimer S, et al. bioRxiv [Preprint]. 2024 Mar 14:2024.03.14.584949. doi: 10.1101/2024.03.14.584949. bioRxiv. 2024. Update in: PLoS Pathog. 2024 Nov 15;20(11):e1012118. doi: 10.1371/journal.ppat.1012118 PMID: 38559167 Free PMC article. Updated. Preprint.
Therapeutically useful mycobacteriophages BPs and Muddy require trehalose polyphleates.
Wetzel KS, Illouz M, Abad L, Aull HG, Russell DA, Garlena RA, Cristinziano M, Malmsheimer S, Chalut C, Hatfull GF, Kremer L. Wetzel KS, et al. Among authors: malmsheimer s. Nat Microbiol. 2023 Sep;8(9):1717-1731. doi: 10.1038/s41564-023-01451-6. Epub 2023 Aug 24. Nat Microbiol. 2023. PMID: 37644325 Free PMC article.
Mycobacterium trehalose polyphleates are required for infection by therapeutically useful mycobacteriophages BPs and Muddy.
Wetzel KS, Illouz M, Abad L, Aull HG, Russell DA, Garlena RA, Cristinziano M, Malmsheimer S, Chalut C, Hatfull GF, Kremer L. Wetzel KS, et al. Among authors: malmsheimer s. bioRxiv [Preprint]. 2023 Jun 3:2023.03.14.532567. doi: 10.1101/2023.03.14.532567. bioRxiv. 2023. Update in: Nat Microbiol. 2023 Sep;8(9):1717-1731. doi: 10.1038/s41564-023-01451-6 PMID: 36993724 Free PMC article. Updated. Preprint.
13 results