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A single-chain variable fragment-based bispecific T-cell activating antibody against CD117 enables T-cell mediated lysis of acute myeloid leukemia and hematopoietic stem and progenitor cells.
Volta L, Myburgh R, Hofstetter M, Koch C, Kiefer JD, Gobbi C, Manfredi F, Zimmermann K, Kaufmann P, Fazio S, Pellegrino C, Russkamp NF, Villars D, Matasci M, Maurer M, Mueller J, Schneiter F, Büschl P, Harrer N, Mock J, Balabanov S, Nombela-Arrieta C, Schroeder T, Neri D, Manz MG. Volta L, et al. Among authors: manz mg. Hemasphere. 2024 Nov 19;8(11):e70055. doi: 10.1002/hem3.70055. eCollection 2024 Nov. Hemasphere. 2024. PMID: 39564539 Free PMC article.
Clonal dynamics after allogeneic haematopoietic cell transplantation.
Spencer Chapman M, Wilk CM, Boettcher S, Mitchell E, Dawson K, Williams N, Müller J, Kovtonyuk L, Jung H, Caiado F, Roberts K, O'Neill L, Kent DG, Green AR, Nangalia J, Manz MG, Campbell PJ. Spencer Chapman M, et al. Among authors: manz mg. Nature. 2024 Nov;635(8040):926-934. doi: 10.1038/s41586-024-08128-y. Epub 2024 Oct 30. Nature. 2024. PMID: 39478227 Free PMC article.
Single-cell landscape of innate and acquired drug resistance in acute myeloid leukemia.
Wegmann R, Bonilla X, Casanova R, Chevrier S, Coelho R, Esposito C, Ficek-Pascual J, Goetze S, Gut G, Jacob F, Jacobs A, Kuipers J, Lischetti U, Mena J, Milani ES, Prummer M, Del Castillo JS, Singer F, Sivapatham S, Toussaint NC, Vilinovszki O, Wildschut MHE, Thavayogarajah T, Malani D; TumorProfiler Consortium; Aebersold R, Bacac M, Beerenwinkel N, Beisel C, Bodenmiller B, Heinzelmann-Schwarz V, Koelzer VH, Levesque MP, Moch H, Pelkmans L, Rätsch G, Tolnay M, Wicki A, Wollscheid B, Manz MG, Snijder B, Theocharides APA. Wegmann R, et al. Among authors: manz mg. Nat Commun. 2024 Oct 30;15(1):9402. doi: 10.1038/s41467-024-53535-4. Nat Commun. 2024. PMID: 39477946 Free PMC article.
Efficient combinatorial adaptor-mediated targeting of acute myeloid leukemia with CAR T-cells.
Volta L, Myburgh R, Pellegrino C, Koch C, Maurer M, Manfredi F, Hofstetter M, Kaiser A, Schneiter F, Müller J, Buehler MM, De Luca R, Favalli N, Magnani CF, Schroeder T, Neri D, Manz MG. Volta L, et al. Among authors: manz mg. Leukemia. 2024 Dec;38(12):2598-2613. doi: 10.1038/s41375-024-02409-1. Epub 2024 Sep 18. Leukemia. 2024. PMID: 39294295 Free PMC article.
538 results