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Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation.
Gilbert LA, Horlbeck MA, Adamson B, Villalta JE, Chen Y, Whitehead EH, Guimaraes C, Panning B, Ploegh HL, Bassik MC, Qi LS, Kampmann M, Weissman JS. Gilbert LA, et al. Among authors: weissman js. Cell. 2014 Oct 23;159(3):647-61. doi: 10.1016/j.cell.2014.09.029. Epub 2014 Oct 9. Cell. 2014. PMID: 25307932 Free PMC article.
Next-generation libraries for robust RNA interference-based genome-wide screens.
Kampmann M, Horlbeck MA, Chen Y, Tsai JC, Bassik MC, Gilbert LA, Villalta JE, Kwon SC, Chang H, Kim VN, Weissman JS. Kampmann M, et al. Among authors: weissman js. Proc Natl Acad Sci U S A. 2015 Jun 30;112(26):E3384-91. doi: 10.1073/pnas.1508821112. Epub 2015 Jun 15. Proc Natl Acad Sci U S A. 2015. PMID: 26080438 Free PMC article.
CRISPR Interference Efficiently Induces Specific and Reversible Gene Silencing in Human iPSCs.
Mandegar MA, Huebsch N, Frolov EB, Shin E, Truong A, Olvera MP, Chan AH, Miyaoka Y, Holmes K, Spencer CI, Judge LM, Gordon DE, Eskildsen TV, Villalta JE, Horlbeck MA, Gilbert LA, Krogan NJ, Sheikh SP, Weissman JS, Qi LS, So PL, Conklin BR. Mandegar MA, et al. Among authors: weissman js. Cell Stem Cell. 2016 Apr 7;18(4):541-53. doi: 10.1016/j.stem.2016.01.022. Epub 2016 Mar 10. Cell Stem Cell. 2016. PMID: 26971820 Free PMC article.
Nucleosomes impede Cas9 access to DNA in vivo and in vitro.
Horlbeck MA, Witkowsky LB, Guglielmi B, Replogle JM, Gilbert LA, Villalta JE, Torigoe SE, Tjian R, Weissman JS. Horlbeck MA, et al. Among authors: weissman js. Elife. 2016 Mar 17;5:e12677. doi: 10.7554/eLife.12677. Elife. 2016. PMID: 26987018 Free PMC article.
CRISPRi-based genome-scale identification of functional long noncoding RNA loci in human cells.
Liu SJ, Horlbeck MA, Cho SW, Birk HS, Malatesta M, He D, Attenello FJ, Villalta JE, Cho MY, Chen Y, Mandegar MA, Olvera MP, Gilbert LA, Conklin BR, Chang HY, Weissman JS, Lim DA. Liu SJ, et al. Among authors: weissman js. Science. 2017 Jan 6;355(6320):aah7111. doi: 10.1126/science.aah7111. Epub 2016 Dec 15. Science. 2017. PMID: 27980086 Free PMC article.
564 results