Weidel E - Search Results

1

Dissecting the Multiple Roles of PqsE in Pseudomonas aeruginosa Virulence by Discovery of Small Tool Compounds.

Zender M, Witzgall F, Drees SL, Weidel E, Maurer CK, Fetzner S, Blankenfeldt W, Empting M, Hartmann RW. Zender M, et al. Among authors: weidel e. ACS Chem Biol. 2016 Jun 17;11(6):1755-63. doi: 10.1021/acschembio.6b00156. Epub 2016 Apr 28. ACS Chem Biol. 2016. PMID: 27082157

2

Biochemical and biophysical analysis of a chiral PqsD inhibitor revealing tight-binding behavior and enantiomers with contrary thermodynamic signatures.

Storz MP, Brengel C, Weidel E, Hoffmann M, Hollemeyer K, Steinbach A, Müller R, Empting M, Hartmann RW. Storz MP, et al. Among authors: weidel e. ACS Chem Biol. 2013 Dec 20;8(12):2794-801. doi: 10.1021/cb400530d. Epub 2013 Oct 25. ACS Chem Biol. 2013. PMID: 24099650

3

Catechol-based substrates of chalcone synthase as a scaffold for novel inhibitors of PqsD.

Allegretta G, Weidel E, Empting M, Hartmann RW. Allegretta G, et al. Among authors: weidel e. Eur J Med Chem. 2015 Jan 27;90:351-9. doi: 10.1016/j.ejmech.2014.11.055. Epub 2014 Nov 27. Eur J Med Chem. 2015. PMID: 25437621 Free article.

4

Exploring the chemical space of ureidothiophene-2-carboxylic acids as inhibitors of the quorum sensing enzyme PqsD from Pseudomonas aeruginosa.

Sahner JH, Empting M, Kamal A, Weidel E, Groh M, Börger C, Hartmann RW. Sahner JH, et al. Among authors: weidel e. Eur J Med Chem. 2015;96:14-21. doi: 10.1016/j.ejmech.2015.04.007. Epub 2015 Apr 6. Eur J Med Chem. 2015. PMID: 25874327

5

Structure optimization of 2-benzamidobenzoic acids as PqsD inhibitors for Pseudomonas aeruginosa infections and elucidation of binding mode by SPR, STD NMR, and molecular docking.

Weidel E, de Jong JC, Brengel C, Storz MP, Braunshausen A, Negri M, Plaza A, Steinbach A, Müller R, Hartmann RW. Weidel E, et al. J Med Chem. 2013 Aug 8;56(15):6146-55. doi: 10.1021/jm4006302. Epub 2013 Jul 19. J Med Chem. 2013. PMID: 23834469

6

Composing compound libraries for hit discovery--rationality-driven preselection or random choice by structural diversity?

Weidel E, Negri M, Empting M, Hinsberger S, Hartmann RW. Weidel E, et al. Future Med Chem. 2014;6(18):2057-72. doi: 10.4155/fmc.14.142. Future Med Chem. 2014. PMID: 25531968

7

Molecular basis of HHQ biosynthesis: molecular dynamics simulations, enzyme kinetic and surface plasmon resonance studies.

Steinbach A, Maurer CK, Weidel E, Henn C, Brengel C, Hartmann RW, Negri M. Steinbach A, et al. Among authors: weidel e. BMC Biophys. 2013 Aug 1;6(1):10. doi: 10.1186/2046-1682-6-10. BMC Biophys. 2013. PMID: 23916145 Free PMC article.

8

Regulation of Burkholderia cenocepacia biofilm formation by RpoN and the c-di-GMP effector BerB.

Fazli M, Rybtke M, Steiner E, Weidel E, Berthelsen J, Groizeleau J, Bin W, Zhi BZ, Yaming Z, Kaever V, Givskov M, Hartmann RW, Eberl L, Tolker-Nielsen T. Fazli M, et al. Among authors: weidel e. Microbiologyopen. 2017 Aug;6(4):e00480. doi: 10.1002/mbo3.480. Epub 2017 Apr 16. Microbiologyopen. 2017. PMID: 28419759 Free PMC article.

9

A rapid method for quantifying chlorogenic acid levels in potato samples.

Weidel E, Schantz M, Richlingi E. Weidel E, et al. J AOAC Int. 2014 May-Jun;97(3):902-7. doi: 10.5740/jaoacint.13-099. J AOAC Int. 2014. PMID: 25051641

10

Analysis of a fused biconical single-mode star coupler.

Eisenmann M, Weidel E. Eisenmann M, et al. Among authors: weidel e. Opt Lett. 1989 Aug 1;14(15):814-6. doi: 10.1364/ol.14.000814. Opt Lett. 1989. PMID: 19752977

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