Bruner JK - Search Results

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All-trans retinoic acid synergizes with FLT3 inhibition to eliminate FLT3/ITD+ leukemia stem cells in vitro and in vivo.

Ma HS, Greenblatt SM, Shirley CM, Duffield AS, Bruner JK, Li L, Nguyen B, Jung E, Aplan PD, Ghiaur G, Jones RJ, Small D. Ma HS, et al. Among authors: bruner jk. Blood. 2016 Jun 9;127(23):2867-78. doi: 10.1182/blood-2015-05-646786. Epub 2016 Apr 21. Blood. 2016. PMID: 27103744 Free PMC article.

Adaptation to TKI Treatment Reactivates ERK Signaling in Tyrosine Kinase-Driven Leukemias and Other Malignancies.

Bruner JK, Ma HS, Li L, Qin ACR, Rudek MA, Jones RJ, Levis MJ, Pratz KW, Pratilas CA, Small D. Bruner JK, et al. Cancer Res. 2017 Oct 15;77(20):5554-5563. doi: 10.1158/0008-5472.CAN-16-2593. Epub 2017 Sep 18. Cancer Res. 2017. PMID: 28923853 Free PMC article.

Targeting rapid TKI-induced AXL upregulation overcomes adaptive ERK reactivation and exerts antileukemic effects in FLT3/ITD acute myeloid leukemia.

Seale TS, Li L, Bruner JK, Chou M, Nguyen B, Seo J, Zhu R, Levis MJ, Pratilas CA, Small D. Seale TS, et al. Among authors: bruner jk. Mol Oncol. 2024 Oct 12. doi: 10.1002/1878-0261.13749. Online ahead of print. Mol Oncol. 2024. PMID: 39395205 Free article.

Identification of novel small molecule modulators of K2P18.1 two-pore potassium channel.

Bruner JK, Zou B, Zhang H, Zhang Y, Schmidt K, Li M. Bruner JK, et al. Eur J Pharmacol. 2014 Oct 5;740:603-10. doi: 10.1016/j.ejphar.2014.06.021. Epub 2014 Jun 24. Eur J Pharmacol. 2014. PMID: 24972239 Free PMC article.

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