Greenblatt SM - Search Results

1

All-trans retinoic acid synergizes with FLT3 inhibition to eliminate FLT3/ITD+ leukemia stem cells in vitro and in vivo.

Ma HS, Greenblatt SM, Shirley CM, Duffield AS, Bruner JK, Li L, Nguyen B, Jung E, Aplan PD, Ghiaur G, Jones RJ, Small D. Ma HS, et al. Among authors: greenblatt sm. Blood. 2016 Jun 9;127(23):2867-78. doi: 10.1182/blood-2015-05-646786. Epub 2016 Apr 21. Blood. 2016. PMID: 27103744 Free PMC article.

2

Effect of FLT3 ligand on survival and disease phenotype in murine models harboring a FLT3 internal tandem duplication mutation.

Bailey EJ, Duffield AS, Greenblatt SM, Aplan PD, Small D. Bailey EJ, et al. Among authors: greenblatt sm. Comp Med. 2013 Jun;63(3):218-26. Comp Med. 2013. PMID: 23759524 Free PMC article.

3

Loss of the wild-type allele contributes to myeloid expansion and disease aggressiveness in FLT3/ITD knockin mice.

Li L, Bailey E, Greenblatt S, Huso D, Small D. Li L, et al. Blood. 2011 Nov 3;118(18):4935-45. doi: 10.1182/blood-2011-01-328096. Epub 2011 Sep 8. Blood. 2011. PMID: 21908433 Free PMC article.

4

Knock-in of a FLT3/ITD mutation cooperates with a NUP98-HOXD13 fusion to generate acute myeloid leukemia in a mouse model.

Greenblatt S, Li L, Slape C, Nguyen B, Novak R, Duffield A, Huso D, Desiderio S, Borowitz MJ, Aplan P, Small D. Greenblatt S, et al. Blood. 2012 Mar 22;119(12):2883-94. doi: 10.1182/blood-2011-10-382283. Epub 2012 Feb 8. Blood. 2012. PMID: 22323452 Free PMC article.

5

FLT3 in lineage specification and plasticity.

Greenblatt S, Small D. Greenblatt S, et al. Oncotarget. 2012 May;3(5):576-80. doi: 10.18632/oncotarget.499. Oncotarget. 2012. PMID: 22643831 Free PMC article.

6

NPMc+ cooperates with Flt3/ITD mutations to cause acute leukemia recapitulating human disease.

Rau R, Magoon D, Greenblatt S, Li L, Annesley C, Duffield AS, Huso D, McIntyre E, Clohessy JG, Reschke M, Pandolfi PP, Small D, Brown P. Rau R, et al. Exp Hematol. 2014 Feb;42(2):101-13.e5. doi: 10.1016/j.exphem.2013.10.005. Epub 2013 Oct 29. Exp Hematol. 2014. PMID: 24184354 Free PMC article.

7

TTT-3002 is a novel FLT3 tyrosine kinase inhibitor with activity against FLT3-associated leukemias in vitro and in vivo.

Ma H, Nguyen B, Li L, Greenblatt S, Williams A, Zhao M, Levis M, Rudek M, Duffield A, Small D. Ma H, et al. Blood. 2014 Mar 6;123(10):1525-34. doi: 10.1182/blood-2013-08-523035. Epub 2014 Jan 9. Blood. 2014. PMID: 24408321 Free PMC article.

8

Caspase-3 controls AML1-ETO-driven leukemogenesis via autophagy modulation in a ULK1-dependent manner.

Man N, Tan Y, Sun XJ, Liu F, Cheng G, Greenblatt SM, Martinez C, Karl DL, Ando K, Sun M, Hou D, Chen B, Xu M, Yang FC, Chen Z, Chen S, Nimer SD, Wang L. Man N, et al. Among authors: greenblatt sm. Blood. 2017 May 18;129(20):2782-2792. doi: 10.1182/blood-2016-10-745034. Epub 2017 Apr 5. Blood. 2017. PMID: 28381396 Free PMC article.

9

Chromatin modifiers and the promise of epigenetic therapy in acute leukemia.

Greenblatt SM, Nimer SD. Greenblatt SM, et al. Leukemia. 2014 Jul;28(7):1396-406. doi: 10.1038/leu.2014.94. Epub 2014 Mar 10. Leukemia. 2014. PMID: 24609046 Free PMC article. Review.

10

TAF1 plays a critical role in AML1-ETO driven leukemogenesis.

Xu Y, Man N, Karl D, Martinez C, Liu F, Sun J, Martinez CJ, Martin GM, Beckedorff F, Lai F, Yue J, Roisman A, Greenblatt S, Duffort S, Wang L, Sun X, Figueroa M, Shiekhattar R, Nimer S. Xu Y, et al. Nat Commun. 2019 Oct 29;10(1):4925. doi: 10.1038/s41467-019-12735-z. Nat Commun. 2019. PMID: 31664040 Free PMC article.

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