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957 results

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Page 1
A novel selective androgen receptor modulator (SARM) MK-4541 exerts anti-androgenic activity in the prostate cancer xenograft R-3327G and anabolic activity on skeletal muscle mass & function in castrated mice.
Chisamore MJ, Gentile MA, Dillon GM, Baran M, Gambone C, Riley S, Schmidt A, Flores O, Wilkinson H, Alves SE. Chisamore MJ, et al. Among authors: riley s. J Steroid Biochem Mol Biol. 2016 Oct;163:88-97. doi: 10.1016/j.jsbmb.2016.04.007. Epub 2016 Apr 19. J Steroid Biochem Mol Biol. 2016. PMID: 27106747
An in vivo evaluation of amphiphilic, biodegradable peptide copolymers as siRNA delivery agents.
Barrett SE, Abrams MT, Burke R, Carr BA, Crocker LS, Garbaccio RM, Howell BJ, Kemp EA, Kowtoniuk RA, Latham AH, Leander KR, Leone AM, Patel M, Pechenov S, Pudvah NT, Riley S, Sepp-Lorenzino L, Walsh ES, Williams JM, Colletti SL. Barrett SE, et al. Among authors: riley s. Int J Pharm. 2014 May 15;466(1-2):58-67. doi: 10.1016/j.ijpharm.2014.03.011. Epub 2014 Mar 5. Int J Pharm. 2014. PMID: 24607208
Development of a liver-targeted siRNA delivery platform with a broad therapeutic window utilizing biodegradable polypeptide-based polymer conjugates.
Barrett SE, Burke RS, Abrams MT, Bason C, Busuek M, Carlini E, Carr BA, Crocker LS, Fan H, Garbaccio RM, Guidry EN, Heo JH, Howell BJ, Kemp EA, Kowtoniuk RA, Latham AH, Leone AM, Lyman M, Parmar RG, Patel M, Pechenov SY, Pei T, Pudvah NT, Raab C, Riley S, Sepp-Lorenzino L, Smith S, Soli ED, Staskiewicz S, Stern M, Truong Q, Vavrek M, Waldman JH, Walsh ES, Williams JM, Young S, Colletti SL. Barrett SE, et al. Among authors: riley s. J Control Release. 2014 Jun 10;183:124-37. doi: 10.1016/j.jconrel.2014.03.028. Epub 2014 Mar 21. J Control Release. 2014. PMID: 24657948
Bitopic Sphingosine 1-Phosphate Receptor 3 (S1P3) Antagonist Rescue from Complete Heart Block: Pharmacological and Genetic Evidence for Direct S1P3 Regulation of Mouse Cardiac Conduction.
Sanna MG, Vincent KP, Repetto E, Nguyen N, Brown SJ, Abgaryan L, Riley SW, Leaf NB, Cahalan SM, Kiosses WB, Kohno Y, Brown JH, McCulloch AD, Rosen H, Gonzalez-Cabrera PJ. Sanna MG, et al. Mol Pharmacol. 2016 Jan;89(1):176-86. doi: 10.1124/mol.115.100222. Epub 2015 Oct 22. Mol Pharmacol. 2016. PMID: 26494861 Free PMC article.
Novel endosomolytic poly(amido amine) polymer conjugates for systemic delivery of siRNA to hepatocytes in rodents and nonhuman primates.
Parmar RG, Poslusney M, Busuek M, Williams JM, Garbaccio R, Leander K, Walsh E, Howell B, Sepp-Lorenzino L, Riley S, Patel M, Kemp E, Latham A, Leone A, Soli E, Burke RS, Carr B, Colletti SL, Wang W. Parmar RG, et al. Among authors: riley s. Bioconjug Chem. 2014 May 21;25(5):896-906. doi: 10.1021/bc400527e. Epub 2014 May 5. Bioconjug Chem. 2014. PMID: 24742200
Novel selective allosteric and bitopic ligands for the S1P(3) receptor.
Jo E, Bhhatarai B, Repetto E, Guerrero M, Riley S, Brown SJ, Kohno Y, Roberts E, Schürer SC, Rosen H. Jo E, et al. Among authors: riley s. ACS Chem Biol. 2012 Dec 21;7(12):1975-83. doi: 10.1021/cb300392z. Epub 2012 Sep 14. ACS Chem Biol. 2012. PMID: 22971058 Free PMC article.
957 results