Suggs JA - Search Results

1

A Restrictive Cardiomyopathy Mutation in an Invariant Proline at the Myosin Head/Rod Junction Enhances Head Flexibility and Function, Yielding Muscle Defects in Drosophila.

Achal M, Trujillo AS, Melkani GC, Farman GP, Ocorr K, Viswanathan MC, Kaushik G, Newhard CS, Glasheen BM, Melkani A, Suggs JA, Moore JR, Swank DM, Bodmer R, Cammarato A, Bernstein SI. Achal M, et al. Among authors: suggs ja. J Mol Biol. 2016 Jun 5;428(11):2446-2461. doi: 10.1016/j.jmb.2016.04.021. Epub 2016 Apr 20. J Mol Biol. 2016. PMID: 27107639 Free PMC article.

2

Assembly of thick filaments and myofibrils occurs in the absence of the myosin head.

Cripps RM, Suggs JA, Bernstein SI. Cripps RM, et al. Among authors: suggs ja. EMBO J. 1999 Apr 1;18(7):1793-804. doi: 10.1093/emboj/18.7.1793. EMBO J. 1999. PMID: 10202143 Free PMC article.

3

The myosin converter domain modulates muscle performance.

Swank DM, Knowles AF, Suggs JA, Sarsoza F, Lee A, Maughan DW, Bernstein SI. Swank DM, et al. Among authors: suggs ja. Nat Cell Biol. 2002 Apr;4(4):312-6. doi: 10.1038/ncb776. Nat Cell Biol. 2002. PMID: 11901423

4

Variable N-terminal regions of muscle myosin heavy chain modulate ATPase rate and actin sliding velocity.

Swank DM, Knowles AF, Kronert WA, Suggs JA, Morrill GE, Nikkhoy M, Manipon GG, Bernstein SI. Swank DM, et al. Among authors: suggs ja. J Biol Chem. 2003 May 9;278(19):17475-82. doi: 10.1074/jbc.M212727200. Epub 2003 Feb 26. J Biol Chem. 2003. PMID: 12606545 Free article.

5

An alternative domain near the nucleotide-binding site of Drosophila muscle myosin affects ATPase kinetics.

Miller BM, Zhang S, Suggs JA, Swank DM, Littlefield KP, Knowles AF, Bernstein SI. Miller BM, et al. Among authors: suggs ja. J Mol Biol. 2005 Oct 14;353(1):14-25. doi: 10.1016/j.jmb.2005.08.012. J Mol Biol. 2005. PMID: 16154586

6

Alternative S2 hinge regions of the myosin rod differentially affect muscle function, myofibril dimensions and myosin tail length.

Suggs JA, Cammarato A, Kronert WA, Nikkhoy M, Dambacher CM, Megighian A, Bernstein SI. Suggs JA, et al. J Mol Biol. 2007 Apr 13;367(5):1312-29. doi: 10.1016/j.jmb.2007.01.045. Epub 2007 Jan 23. J Mol Biol. 2007. PMID: 17316684 Free PMC article.

7

Drosophila UNC-45 accumulates in embryonic blastoderm and in muscles, and is essential for muscle myosin stability.

Lee CF, Melkani GC, Yu Q, Suggs JA, Kronert WA, Suzuki Y, Hipolito L, Price MG, Epstein HF, Bernstein SI. Lee CF, et al. Among authors: suggs ja. J Cell Sci. 2011 Mar 1;124(Pt 5):699-705. doi: 10.1242/jcs.078964. Epub 2011 Feb 1. J Cell Sci. 2011. PMID: 21285246 Free PMC article.

8

Expression of the inclusion body myopathy 3 mutation in Drosophila depresses myosin function and stability and recapitulates muscle inclusions and weakness.

Wang Y, Melkani GC, Suggs JA, Melkani A, Kronert WA, Cammarato A, Bernstein SI. Wang Y, et al. Among authors: suggs ja. Mol Biol Cell. 2012 Jun;23(11):2057-65. doi: 10.1091/mbc.E12-02-0120. Epub 2012 Apr 11. Mol Biol Cell. 2012. PMID: 22496423 Free PMC article.

9

The NADPH metabolic network regulates human αB-crystallin cardiomyopathy and reductive stress in Drosophila melanogaster.

Xie HB, Cammarato A, Rajasekaran NS, Zhang H, Suggs JA, Lin HC, Bernstein SI, Benjamin IJ, Golic KG. Xie HB, et al. Among authors: suggs ja. PLoS Genet. 2013 Jun;9(6):e1003544. doi: 10.1371/journal.pgen.1003544. Epub 2013 Jun 20. PLoS Genet. 2013. PMID: 23818860 Free PMC article.

10

X-ray diffraction from flight muscle with a headless myosin mutation: implications for interpreting reflection patterns.

Iwamoto H, Trombitás K, Yagi N, Suggs JA, Bernstein SI. Iwamoto H, et al. Among authors: suggs ja. Front Physiol. 2014 Oct 29;5:416. doi: 10.3389/fphys.2014.00416. eCollection 2014. Front Physiol. 2014. PMID: 25400584 Free PMC article.

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