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Page 1
Synthesis of a stable and orally bioavailable englerin analogue.
Fash DM, Peer CJ, Li Z, Talisman IJ, Hayavi S, Sulzmaier FJ, Ramos JW, Sourbier C, Neckers L, Figg WD, Beutler JA, Chain WJ. Fash DM, et al. Among authors: sourbier c. Bioorg Med Chem Lett. 2016 Jun 1;26(11):2641-4. doi: 10.1016/j.bmcl.2016.04.016. Epub 2016 Apr 8. Bioorg Med Chem Lett. 2016. PMID: 27107948 Free PMC article.
Molecular chaperone TRAP1 regulates a metabolic switch between mitochondrial respiration and aerobic glycolysis.
Yoshida S, Tsutsumi S, Muhlebach G, Sourbier C, Lee MJ, Lee S, Vartholomaiou E, Tatokoro M, Beebe K, Miyajima N, Mohney RP, Chen Y, Hasumi H, Xu W, Fukushima H, Nakamura K, Koga F, Kihara K, Trepel J, Picard D, Neckers L. Yoshida S, et al. Among authors: sourbier c. Proc Natl Acad Sci U S A. 2013 Apr 23;110(17):E1604-12. doi: 10.1073/pnas.1220659110. Epub 2013 Apr 5. Proc Natl Acad Sci U S A. 2013. PMID: 23564345 Free PMC article.
Lack of mitochondrial topoisomerase I (TOP1mt) impairs liver regeneration.
Khiati S, Baechler SA, Factor VM, Zhang H, Huang SY, Dalla Rosa I, Sourbier C, Neckers L, Thorgeirsson SS, Pommier Y. Khiati S, et al. Among authors: sourbier c. Proc Natl Acad Sci U S A. 2015 Sep 8;112(36):11282-7. doi: 10.1073/pnas.1511016112. Epub 2015 Aug 24. Proc Natl Acad Sci U S A. 2015. PMID: 26305952 Free PMC article.
The mitochondrial type IB topoisomerase drives mitochondrial translation and carcinogenesis.
Baechler SA, Factor VM, Dalla Rosa I, Ravji A, Becker D, Khiati S, Miller Jenkins LM, Lang M, Sourbier C, Michaels SA, Neckers LM, Zhang HL, Spinazzola A, Huang SN, Marquardt JU, Pommier Y. Baechler SA, et al. Among authors: sourbier c. Nat Commun. 2019 Jan 8;10(1):83. doi: 10.1038/s41467-018-07922-3. Nat Commun. 2019. PMID: 30622257 Free PMC article.
Novel renal medullary carcinoma cell lines, UOK353 and UOK360, provide preclinical tools to identify new therapeutic treatments.
Wei D, Yang Y, Ricketts CJ, Vocke CD, Ball MW, Sourbier C, Wangsa D, Wangsa D, Guha R, Zhang X, Wilson K, Chen L, Meltzer PS, Ried T, Thomas CJ, Merino MJ, Linehan WM. Wei D, et al. Among authors: sourbier c. Genes Chromosomes Cancer. 2020 Aug;59(8):472-483. doi: 10.1002/gcc.22847. Epub 2020 Apr 17. Genes Chromosomes Cancer. 2020. PMID: 32259323 Free PMC article.
58 results