Gao JR - Search Results

1

A novel GSK-3β inhibitor YQ138 prevents neuronal injury induced by glutamate and brain ischemia through activation of the Nrf2 signaling pathway.

Pang T, Wang YJ, Gao YX, Xu Y, Li Q, Zhou YB, Xu L, Huang ZJ, Liao H, Zhang LY, Gao JR, Ye Q, Li J. Pang T, et al. Among authors: gao yx, gao jr. Acta Pharmacol Sin. 2016 Jun;37(6):741-52. doi: 10.1038/aps.2016.3. Epub 2016 Apr 25. Acta Pharmacol Sin. 2016. PMID: 27108601 Free PMC article.

2

Synthesis and biological evaluation of 3-benzisoxazolyl-4-indolylmaleimides as potent, selective inhibitors of glycogen synthase kinase-3β.

Ye Q, Li M, Zhou Y, Pang T, Xu L, Cao J, Han L, Li Y, Wang W, Gao J, Li J. Ye Q, et al. Molecules. 2013 May 13;18(5):5498-516. doi: 10.3390/molecules18055498. Molecules. 2013. PMID: 23669633 Free PMC article.

3

Synthesis and biological evaluation of 3-([1,2,4]triazolo[4,3-a]pyridin-3-yl)-4-(indol-3-yl)-maleimides as potent, selective GSK-3β inhibitors and neuroprotective agents.

Ye Q, Mao W, Zhou Y, Xu L, Li Q, Gao Y, Wang J, Li C, Xu Y, Xu Y, Liao H, Zhang L, Gao J, Li J, Pang T. Ye Q, et al. Bioorg Med Chem. 2015 Mar 1;23(5):1179-88. doi: 10.1016/j.bmc.2014.12.026. Epub 2014 Dec 20. Bioorg Med Chem. 2015. PMID: 25662701

4

Synthesis and Evaluation of 3-(furo[2,3-b]pyridin-3-yl)-4-(1H-indol-3-yl)-maleimides as Novel GSK-3β Inhibitors and Anti-Ischemic Agents.

Ye Q, Li Q, Zhou Y, Xu L, Mao W, Gao Y, Li C, Xu Y, Xu Y, Liao H, Zhang L, Gao J, Li J, Pang T. Ye Q, et al. Chem Biol Drug Des. 2015 Oct;86(4):746-52. doi: 10.1111/cbdd.12546. Epub 2015 Mar 16. Chem Biol Drug Des. 2015. PMID: 25711384

5

Design, synthesis and evaluation of 7-azaindazolyl-indolyl-maleimides as glycogen synthase kinase-3β (GSK-3β) inhibitors.

Ye Q, Shen Y, Zhou Y, Lv D, Gao J, Li J, Hu Y. Ye Q, et al. Eur J Med Chem. 2013 Oct;68:361-71. doi: 10.1016/j.ejmech.2013.07.046. Epub 2013 Aug 9. Eur J Med Chem. 2013. PMID: 23994329

6

Synthesis and biological evaluation of 3-aryl-4-indolyl-maleimides as potent mutant isocitrate dehydrogenase-1 inhibitors.

Liu X, Hu Y, Gao A, Xu M, Gao L, Xu L, Zhou Y, Gao J, Ye Q, Li J. Liu X, et al. Bioorg Med Chem. 2019 Feb 15;27(4):589-603. doi: 10.1016/j.bmc.2018.12.029. Epub 2018 Dec 23. Bioorg Med Chem. 2019. PMID: 30600148

7

Design, synthesis, and evaluation of 3-aryl-4-pyrrolyl-maleimides as glycogen synthase kinase-3β inhibitors.

Ye Q, Li M, Zhou YB, Cao JY, Xu L, Li YJ, Han L, Gao JR, Hu YZ, Li J. Ye Q, et al. Among authors: gao jr. Arch Pharm (Weinheim). 2013 May;346(5):349-58. doi: 10.1002/ardp.201300008. Epub 2013 Apr 15. Arch Pharm (Weinheim). 2013. PMID: 23585245

8

Synthesis and biological evaluation of novel 4,5-bisindolyl-1,2,4-triazol-3-ones as glycogen synthase kinase-3β inhibitors and neuroprotective agents.

Hu Y, Ruan W, Gao A, Zhou Y, Gao L, Xu M, Gao J, Ye Q, Li J, Pang T. Hu Y, et al. Pharmazie. 2017 Dec 1;72(12):707-713. doi: 10.1691/ph.2017.7722. Pharmazie. 2017. PMID: 29441954

9

3-(7-Azaindolyl)-4-indolylmaleimides as a novel class of mutant isocitrate dehydrogenase-1 inhibitors: Design, synthesis, and biological evaluation.

Hu Y, Gao A, Liao H, Zhang M, Xu G, Gao L, Xu L, Zhou Y, Gao J, Ye Q, Li J. Hu Y, et al. Arch Pharm (Weinheim). 2018 Oct;351(10):e1800039. doi: 10.1002/ardp.201800039. Epub 2018 Aug 16. Arch Pharm (Weinheim). 2018. PMID: 30113716

10

The synthesis of benzo[f]isoindole-1,3-dicarboxylates via an i2-induced 1,3-dipolar cycloaddition reaction.

Li YJ, Huang HM, Dong HQ, Jia JH, Han L, Ye Q, Gao JR. Li YJ, et al. Among authors: gao jr. J Org Chem. 2013 Sep 20;78(18):9424-30. doi: 10.1021/jo401652k. Epub 2013 Sep 11. J Org Chem. 2013. PMID: 23977993

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