Huang ZJ - Search Results

1

A novel GSK-3β inhibitor YQ138 prevents neuronal injury induced by glutamate and brain ischemia through activation of the Nrf2 signaling pathway.

Pang T, Wang YJ, Gao YX, Xu Y, Li Q, Zhou YB, Xu L, Huang ZJ, Liao H, Zhang LY, Gao JR, Ye Q, Li J. Pang T, et al. Among authors: huang zj. Acta Pharmacol Sin. 2016 Jun;37(6):741-52. doi: 10.1038/aps.2016.3. Epub 2016 Apr 25. Acta Pharmacol Sin. 2016. PMID: 27108601 Free PMC article.

2

Synthesis and anti-human hepatocellular carcinoma activity of new nitric oxide-releasing glycosyl derivatives of oleanolic acid.

Huang Z, Zhang Y, Zhao L, Jing Y, Lai Y, Zhang L, Guo Q, Yuan S, Zhang J, Chen L, Peng S, Tian J. Huang Z, et al. Org Biomol Chem. 2010 Feb 7;8(3):632-9. doi: 10.1039/b918846k. Epub 2009 Dec 8. Org Biomol Chem. 2010. PMID: 20090981

3

Design, synthesis and evaluation of tacrine-flurbiprofen-nitrate trihybrids as novel anti-Alzheimer's disease agents.

Chen Y, Sun J, Huang Z, Liao H, Peng S, Lehmann J, Zhang Y. Chen Y, et al. Bioorg Med Chem. 2013 May 1;21(9):2462-70. doi: 10.1016/j.bmc.2013.03.005. Epub 2013 Mar 13. Bioorg Med Chem. 2013. PMID: 23541836

4

NO-donating tacrine derivatives as potential butyrylcholinesterase inhibitors with vasorelaxation activity.

Chen Y, Sun J, Huang Z, Liao H, Peng S, Lehmann J, Zhang Y. Chen Y, et al. Bioorg Med Chem Lett. 2013 Jun 1;23(11):3162-5. doi: 10.1016/j.bmcl.2013.04.008. Epub 2013 Apr 10. Bioorg Med Chem Lett. 2013. PMID: 23639542

5

The edaravone and 3-n-butylphthalide ring-opening derivative 10b effectively attenuates cerebral ischemia injury in rats.

Hua K, Sheng X, Li TT, Wang LN, Zhang YH, Huang ZJ, Ji H. Hua K, et al. Among authors: huang zj. Acta Pharmacol Sin. 2015 Aug;36(8):917-27. doi: 10.1038/aps.2015.31. Epub 2015 Jun 15. Acta Pharmacol Sin. 2015. PMID: 26073328 Free PMC article.

6

Telmisartan prevention of LPS-induced microglia activation involves M2 microglia polarization via CaMKKβ-dependent AMPK activation.

Xu Y, Xu Y, Wang Y, Wang Y, He L, Jiang Z, Huang Z, Liao H, Li J, Saavedra JM, Zhang L, Pang T. Xu Y, et al. Brain Behav Immun. 2015 Nov;50:298-313. doi: 10.1016/j.bbi.2015.07.015. Epub 2015 Jul 16. Brain Behav Immun. 2015. PMID: 26188187

7

Totarol prevents neuronal injury in vitro and ameliorates brain ischemic stroke: Potential roles of Akt activation and HO-1 induction.

Gao Y, Xu X, Chang S, Wang Y, Xu Y, Ran S, Huang Z, Li P, Li J, Zhang L, Saavedra JM, Liao H, Pang T. Gao Y, et al. Toxicol Appl Pharmacol. 2015 Dec 1;289(2):142-54. doi: 10.1016/j.taap.2015.10.001. Epub 2015 Oct 9. Toxicol Appl Pharmacol. 2015. PMID: 26440581

8

A Dual AMPK/Nrf2 Activator Reduces Brain Inflammation After Stroke by Enhancing Microglia M2 Polarization.

Wang Y, Huang Y, Xu Y, Ruan W, Wang H, Zhang Y, Saavedra JM, Zhang L, Huang Z, Pang T. Wang Y, et al. Antioxid Redox Signal. 2018 Jan 10;28(2):141-163. doi: 10.1089/ars.2017.7003. Epub 2017 Aug 29. Antioxid Redox Signal. 2018. PMID: 28747068

9

Tetrazine-mediated bioorthogonal removal of 3-isocyanopropyl groups enables the controlled release of nitric oxide in vivo.

Wu J, Sun T, Yang C, Lv T, Bi Y, Xu Y, Ling Y, Zhao J, Cong R, Zhang Y, Wang J, Wen H, Jiang H, Li F, Huang Z. Wu J, et al. Biomater Sci. 2021 Mar 10;9(5):1816-1825. doi: 10.1039/d0bm01841d. Biomater Sci. 2021. PMID: 33458722

10

Design, Synthesis, and Biological Evaluation of Organic Nitrite (NO₂^-) Donors as Potential Anticerebral Ischemia Agents.

Wu J, Yin W, Huang Z, Zhang Y, Jia J, Cheng H, Kang F, Huang K, Sun T, Tian J, Xu X, Zhang Y. Wu J, et al. J Med Chem. 2021 Aug 12;64(15):10919-10933. doi: 10.1021/acs.jmedchem.1c00282. Epub 2021 Jul 22. J Med Chem. 2021. PMID: 34292749

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