Kurahashi K - Search Results

1

Deazaflavin Inhibitors of Tyrosyl-DNA Phosphodiesterase 2 (TDP2) Specific for the Human Enzyme and Active against Cellular TDP2.

Marchand C, Abdelmalak M, Kankanala J, Huang SY, Kiselev E, Fesen K, Kurahashi K, Sasanuma H, Takeda S, Aihara H, Wang Z, Pommier Y. Marchand C, et al. Among authors: kurahashi k. ACS Chem Biol. 2016 Jul 15;11(7):1925-33. doi: 10.1021/acschembio.5b01047. Epub 2016 May 11. ACS Chem Biol. 2016. PMID: 27128689 Free PMC article.

2

Structural basis for recognition of 5'-phosphotyrosine adducts by Tdp2.

Shi K, Kurahashi K, Gao R, Tsutakawa SE, Tainer JA, Pommier Y, Aihara H. Shi K, et al. Among authors: kurahashi k. Nat Struct Mol Biol. 2012 Dec;19(12):1372-7. doi: 10.1038/nsmb.2423. Epub 2012 Oct 28. Nat Struct Mol Biol. 2012. PMID: 23104058 Free PMC article.

3

New fluorescence-based high-throughput screening assay for small molecule inhibitors of tyrosyl-DNA phosphodiesterase 2 (TDP2).

Ribeiro CJA, Kankanala J, Shi K, Kurahashi K, Kiselev E, Ravji A, Pommier Y, Aihara H, Wang Z. Ribeiro CJA, et al. Among authors: kurahashi k. Eur J Pharm Sci. 2018 Jun 15;118:67-79. doi: 10.1016/j.ejps.2018.03.021. Epub 2018 Mar 21. Eur J Pharm Sci. 2018. PMID: 29574079 Free PMC article.

4

Crystal Structure of the DNA Deaminase APOBEC3B Catalytic Domain.

Shi K, Carpenter MA, Kurahashi K, Harris RS, Aihara H. Shi K, et al. Among authors: kurahashi k. J Biol Chem. 2015 Nov 20;290(47):28120-28130. doi: 10.1074/jbc.M115.679951. Epub 2015 Sep 28. J Biol Chem. 2015. PMID: 26416889 Free PMC article.

5

The substrate-binding cap of the UDP-diacylglucosamine pyrophosphatase LpxH is highly flexible, enabling facile substrate binding and product release.

Bohl HO, Ieong P, Lee JK, Lee T, Kankanala J, Shi K, Demir Ö, Kurahashi K, Amaro RE, Wang Z, Aihara H. Bohl HO, et al. Among authors: kurahashi k. J Biol Chem. 2018 May 25;293(21):7969-7981. doi: 10.1074/jbc.RA118.002503. Epub 2018 Apr 6. J Biol Chem. 2018. PMID: 29626094 Free PMC article.

6

An ancient protein-DNA interaction underlying metazoan sex determination.

Murphy MW, Lee JK, Rojo S, Gearhart MD, Kurahashi K, Banerjee S, Loeuille GA, Bashamboo A, McElreavey K, Zarkower D, Aihara H, Bardwell VJ. Murphy MW, et al. Among authors: kurahashi k. Nat Struct Mol Biol. 2015 Jun;22(6):442-51. doi: 10.1038/nsmb.3032. Epub 2015 May 25. Nat Struct Mol Biol. 2015. PMID: 26005864 Free PMC article.

7

Crystal Structure of Entamoeba histolytica Cdc45 Suggests a Conformational Switch that May Regulate DNA Replication.

Kurniawan F, Shi K, Kurahashi K, Bielinsky AK, Aihara H. Kurniawan F, et al. Among authors: kurahashi k. iScience. 2018 May 25;3:102-109. doi: 10.1016/j.isci.2018.04.011. iScience. 2018. PMID: 29901028 Free PMC article.

8

Conformational Switch Regulates the DNA Cytosine Deaminase Activity of Human APOBEC3B.

Shi K, Demir Ö, Carpenter MA, Wagner J, Kurahashi K, Harris RS, Amaro RE, Aihara H. Shi K, et al. Among authors: kurahashi k. Sci Rep. 2017 Dec 12;7(1):17415. doi: 10.1038/s41598-017-17694-3. Sci Rep. 2017. PMID: 29234087 Free PMC article.

9

Structural basis for targeted DNA cytosine deamination and mutagenesis by APOBEC3A and APOBEC3B.

Shi K, Carpenter MA, Banerjee S, Shaban NM, Kurahashi K, Salamango DJ, McCann JL, Starrett GJ, Duffy JV, Demir Ö, Amaro RE, Harki DA, Harris RS, Aihara H. Shi K, et al. Among authors: kurahashi k. Nat Struct Mol Biol. 2017 Feb;24(2):131-139. doi: 10.1038/nsmb.3344. Epub 2016 Dec 19. Nat Struct Mol Biol. 2017. PMID: 27991903 Free PMC article.

10

The FHA domain determines Drosophila Chk2/Mnk localization to key mitotic structures and is essential for early embryonic DNA damage responses.

Takada S, Collins ER, Kurahashi K. Takada S, et al. Among authors: kurahashi k. Mol Biol Cell. 2015 May 15;26(10):1811-28. doi: 10.1091/mbc.E14-07-1238. Epub 2015 Mar 25. Mol Biol Cell. 2015. PMID: 25808488 Free PMC article.

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