Westwell AD - Search Results

1

Design and synthesis of novel bicalutamide and enzalutamide derivatives as antiproliferative agents for the treatment of prostate cancer.

Bassetto M, Ferla S, Pertusati F, Kandil S, Westwell AD, Brancale A, McGuigan C. Bassetto M, et al. Among authors: westwell ad. Eur J Med Chem. 2016 Aug 8;118:230-43. doi: 10.1016/j.ejmech.2016.04.052. Epub 2016 Apr 22. Eur J Med Chem. 2016. PMID: 27131065 Free article.

2

Antitumour benzothiazoles. Part 10: the synthesis and antitumour activity of benzothiazole substituted quinol derivatives.

Wells G, Bradshaw TD, Diana P, Seaton A, Shi DF, Westwell AD, Stevens MF. Wells G, et al. Among authors: westwell ad. Bioorg Med Chem Lett. 2000 Mar 6;10(5):513-5. doi: 10.1016/s0960-894x(00)00027-5. Bioorg Med Chem Lett. 2000. PMID: 10743960

3

Antitumor benzothiazoles. 14. Synthesis and in vitro biological properties of fluorinated 2-(4-aminophenyl)benzothiazoles.

Hutchinson I, Chua MS, Browne HL, Trapani V, Bradshaw TD, Westwell AD, Stevens MF. Hutchinson I, et al. Among authors: westwell ad. J Med Chem. 2001 Apr 26;44(9):1446-55. doi: 10.1021/jm001104n. J Med Chem. 2001. PMID: 11311068

4

4-Substituted 4-hydroxycyclohexa-2,5-dien-1-ones with selective activities against colon and renal cancer cell lines.

Wells G, Berry JM, Bradshaw TD, Burger AM, Seaton A, Wang B, Westwell AD, Stevens MF. Wells G, et al. Among authors: westwell ad. J Med Chem. 2003 Feb 13;46(4):532-41. doi: 10.1021/jm020984y. J Med Chem. 2003. PMID: 12570375

5

Synthesis, antitumor evaluation, and apoptosis-inducing activity of hydroxylated (E)-stilbenes.

Lion CJ, Matthews CS, Stevens MF, Westwell AD. Lion CJ, et al. Among authors: westwell ad. J Med Chem. 2005 Feb 24;48(4):1292-5. doi: 10.1021/jm049238e. J Med Chem. 2005. PMID: 15715501

6

Antitumor benzothiazoles. 26.(1) 2-(3,4-dimethoxyphenyl)-5-fluorobenzothiazole (GW 610, NSC 721648), a simple fluorinated 2-arylbenzothiazole, shows potent and selective inhibitory activity against lung, colon, and breast cancer cell lines.

Mortimer CG, Wells G, Crochard JP, Stone EL, Bradshaw TD, Stevens MF, Westwell AD. Mortimer CG, et al. Among authors: westwell ad. J Med Chem. 2006 Jan 12;49(1):179-85. doi: 10.1021/jm050942k. J Med Chem. 2006. PMID: 16392802

7

Antitumour properties of fluorinated benzothiazole-substituted hydroxycyclohexa-2,5-dienones ('quinols').

Lion CJ, Matthews CS, Wells G, Bradshaw TD, Stevens MF, Westwell AD. Lion CJ, et al. Among authors: westwell ad. Bioorg Med Chem Lett. 2006 Oct 1;16(19):5005-8. doi: 10.1016/j.bmcl.2006.07.072. Bioorg Med Chem Lett. 2006. PMID: 16908135

8

Quinols as novel therapeutic agents. 7.1 Synthesis of antitumor 4-[1-(arylsulfonyl-1H-indol-2-yl)]-4-hydroxycyclohexa-2,5-dien-1-ones by Sonogashira reactions.

McCarroll AJ, Bradshaw TD, Westwell AD, Matthews CS, Stevens MF. McCarroll AJ, et al. Among authors: westwell ad. J Med Chem. 2007 Apr 5;50(7):1707-10. doi: 10.1021/jm061163m. Epub 2007 Mar 8. J Med Chem. 2007. PMID: 17343370

9

The development of pro-apoptotic cancer therapeutics.

Ziedan NI, Kadri H, Westwell AD. Ziedan NI, et al. Among authors: westwell ad. Mini Rev Med Chem. 2008 Jun;8(7):711-8. doi: 10.2174/138955708784567430. Mini Rev Med Chem. 2008. PMID: 18537726 Review.

10

Synthesis and biological properties of benzothiazole, benzoxazole, and chromen-4-one analogues of the potent antitumor agent 2-(3,4-dimethoxyphenyl)-5-fluorobenzothiazole (PMX 610, NSC 721648).

Aiello S, Wells G, Stone EL, Kadri H, Bazzi R, Bell DR, Stevens MF, Matthews CS, Bradshaw TD, Westwell AD. Aiello S, et al. Among authors: westwell ad. J Med Chem. 2008 Aug 28;51(16):5135-9. doi: 10.1021/jm800418z. Epub 2008 Jul 31. J Med Chem. 2008. PMID: 18666770

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