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Muscle-specific kinase myasthenia gravis IgG4 autoantibodies cause severe neuromuscular junction dysfunction in mice.
Klooster R, Plomp JJ, Huijbers MG, Niks EH, Straasheijm KR, Detmers FJ, Hermans PW, Sleijpen K, Verrips A, Losen M, Martinez-Martinez P, De Baets MH, van der Maarel SM, Verschuuren JJ. Klooster R, et al. Among authors: huijbers mg. Brain. 2012 Apr;135(Pt 4):1081-101. doi: 10.1093/brain/aws025. Epub 2012 Mar 6. Brain. 2012. PMID: 22396395
Pathophysiology of myasthenia gravis with antibodies to the acetylcholine receptor, muscle-specific kinase and low-density lipoprotein receptor-related protein 4.
Verschuuren JJ, Huijbers MG, Plomp JJ, Niks EH, Molenaar PC, Martinez-Martinez P, Gomez AM, De Baets MH, Losen M. Verschuuren JJ, et al. Among authors: huijbers mg. Autoimmun Rev. 2013 Jul;12(9):918-23. doi: 10.1016/j.autrev.2013.03.001. Epub 2013 Mar 25. Autoimmun Rev. 2013. PMID: 23535160 Review.
MuSK IgG4 autoantibodies cause myasthenia gravis by inhibiting binding between MuSK and Lrp4.
Huijbers MG, Zhang W, Klooster R, Niks EH, Friese MB, Straasheijm KR, Thijssen PE, Vrolijk H, Plomp JJ, Vogels P, Losen M, Van der Maarel SM, Burden SJ, Verschuuren JJ. Huijbers MG, et al. Proc Natl Acad Sci U S A. 2013 Dec 17;110(51):20783-8. doi: 10.1073/pnas.1313944110. Epub 2013 Dec 2. Proc Natl Acad Sci U S A. 2013. PMID: 24297891 Free PMC article. Clinical Trial.
Cortactin autoantibodies in myasthenia gravis.
Gallardo E, Martínez-Hernández E, Titulaer MJ, Huijbers MG, Martínez MA, Ramos A, Querol L, Díaz-Manera J, Rojas-García R, Hayworth CR, Verschuuren JJ, Balice-Gordon R, Dalmau J, Illa I. Gallardo E, et al. Among authors: huijbers mg. Autoimmun Rev. 2014 Oct;13(10):1003-7. doi: 10.1016/j.autrev.2014.08.039. Epub 2014 Sep 3. Autoimmun Rev. 2014. PMID: 25193850
Longitudinal epitope mapping in MuSK myasthenia gravis: implications for disease severity.
Huijbers MG, Vink AF, Niks EH, Westhuis RH, van Zwet EW, de Meel RH, Rojas-García R, Díaz-Manera J, Kuks JB, Klooster R, Straasheijm K, Evoli A, Illa I, van der Maarel SM, Verschuuren JJ. Huijbers MG, et al. J Neuroimmunol. 2016 Feb 15;291:82-8. doi: 10.1016/j.jneuroim.2015.12.016. Epub 2016 Jan 5. J Neuroimmunol. 2016. PMID: 26857500
43 results