El-Samad H - Search Results

1

Low Dimensionality in Gene Expression Data Enables the Accurate Extraction of Transcriptional Programs from Shallow Sequencing.

Heimberg G, Bhatnagar R, El-Samad H, Thomson M. Heimberg G, et al. Cell Syst. 2016 Apr 27;2(4):239-250. doi: 10.1016/j.cels.2016.04.001. Epub 2016 Apr 27. Cell Syst. 2016. PMID: 27135536 Free PMC article.

2

Robust Synthetic Circuits for Two-Dimensional Control of Gene Expression in Yeast.

Aranda-Díaz A, Mace K, Zuleta I, Harrigan P, El-Samad H. Aranda-Díaz A, et al. ACS Synth Biol. 2017 Mar 17;6(3):545-554. doi: 10.1021/acssynbio.6b00251. Epub 2016 Dec 27. ACS Synth Biol. 2017. PMID: 27930885 Free PMC article.

3

Model-guided optogenetic study of PKA signaling in budding yeast.

Stewart-Ornstein J, Chen S, Bhatnagar R, Weissman JS, El-Samad H. Stewart-Ornstein J, et al. Mol Biol Cell. 2017 Jan 1;28(1):221-227. doi: 10.1091/mbc.E16-06-0354. Epub 2016 Nov 9. Mol Biol Cell. 2017. PMID: 28035051 Free PMC article.

4

Optogenetic Control Reveals Differential Promoter Interpretation of Transcription Factor Nuclear Translocation Dynamics.

Chen SY, Osimiri LC, Chevalier M, Bugaj LJ, Nguyen TH, Greenstein RA, Ng AH, Stewart-Ornstein J, Neves LT, El-Samad H. Chen SY, et al. Cell Syst. 2020 Oct 21;11(4):336-353.e24. doi: 10.1016/j.cels.2020.08.009. Epub 2020 Sep 7. Cell Syst. 2020. PMID: 32898473 Free PMC article.

5

TRADEOFFS IN ADAPTING BIOLOGICAL SYSTEMS.

Bhatnagar R, El-Samad H. Bhatnagar R, et al. Eur J Control. 2016 Jul;30:68-75. doi: 10.1016/j.ejcon.2016.04.010. Epub 2016 May 13. Eur J Control. 2016. PMID: 33100592 Free PMC article.

6

Biological feedback control-Respect the loops.

El-Samad H. El-Samad H. Cell Syst. 2021 Jun 16;12(6):477-487. doi: 10.1016/j.cels.2021.05.004. Cell Syst. 2021. PMID: 34139160 Free article. Review.

7

Coordinate control of gene expression noise and interchromosomal interactions in a MAP kinase pathway.

McCullagh E, Seshan A, El-Samad H, Madhani HD. McCullagh E, et al. Nat Cell Biol. 2010 Oct;12(10):954-62. doi: 10.1038/ncb2097. Epub 2010 Sep 19. Nat Cell Biol. 2010. PMID: 20852627 Free PMC article.

8

Can a systems perspective help us appreciate the biological meaning of small effects?

El-Samad H, Madhani HD. El-Samad H, et al. Dev Cell. 2011 Jul 19;21(1):11-3. doi: 10.1016/j.devcel.2011.06.005. Dev Cell. 2011. PMID: 21763599 Free PMC article.

9

Cellular noise regulons underlie fluctuations in Saccharomyces cerevisiae.

Stewart-Ornstein J, Weissman JS, El-Samad H. Stewart-Ornstein J, et al. Mol Cell. 2012 Feb 24;45(4):483-93. doi: 10.1016/j.molcel.2011.11.035. Mol Cell. 2012. PMID: 22365828 Free PMC article.

10

Stochastic modeling of cellular networks.

Stewart-Ornstein J, El-Samad H. Stewart-Ornstein J, et al. Methods Cell Biol. 2012;110:111-37. doi: 10.1016/B978-0-12-388403-9.00005-9. Methods Cell Biol. 2012. PMID: 22482947

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