Sormanni P - Search Results

1

Rational design of mutations that change the aggregation rate of a protein while maintaining its native structure and stability.

Camilloni C, Sala BM, Sormanni P, Porcari R, Corazza A, De Rosa M, Zanini S, Barbiroli A, Esposito G, Bolognesi M, Bellotti V, Vendruscolo M, Ricagno S. Camilloni C, et al. Among authors: sormanni p. Sci Rep. 2016 May 6;6:25559. doi: 10.1038/srep25559. Sci Rep. 2016. PMID: 27150430 Free PMC article.

2

Approaches to expand the conventional toolbox for discovery and selection of antibodies with drug-like physicochemical properties.

Svilenov HL, Arosio P, Menzen T, Tessier P, Sormanni P. Svilenov HL, et al. Among authors: sormanni p. MAbs. 2023 Jan-Dec;15(1):2164459. doi: 10.1080/19420862.2022.2164459. MAbs. 2023. PMID: 36629855 Free PMC article.

3

Fibrillogenic propensity of the GroEL apical domain: a Janus-faced minichaperone.

Chen J, Yagi H, Sormanni P, Vendruscolo M, Makabe K, Nakamura T, Goto Y, Kuwajima K. Chen J, et al. Among authors: sormanni p. FEBS Lett. 2012 Apr 24;586(8):1120-7. doi: 10.1016/j.febslet.2012.03.019. Epub 2012 Mar 23. FEBS Lett. 2012. PMID: 22575645 Free article.

4

Subdomain architecture and stability of a giant repeat protein.

Tsytlonok M, Sormanni P, Rowling PJ, Vendruscolo M, Itzhaki LS. Tsytlonok M, et al. Among authors: sormanni p. J Phys Chem B. 2013 Oct 24;117(42):13029-37. doi: 10.1021/jp402360x. Epub 2013 Sep 20. J Phys Chem B. 2013. PMID: 24053231

5

Understanding the frustration arising from the competition between function, misfolding, and aggregation in a globular protein.

Gianni S, Camilloni C, Giri R, Toto A, Bonetti D, Morrone A, Sormanni P, Brunori M, Vendruscolo M. Gianni S, et al. Among authors: sormanni p. Proc Natl Acad Sci U S A. 2014 Sep 30;111(39):14141-6. doi: 10.1073/pnas.1405233111. Epub 2014 Sep 16. Proc Natl Acad Sci U S A. 2014. PMID: 25228761 Free PMC article.

6

The CamSol method of rational design of protein mutants with enhanced solubility.

Sormanni P, Aprile FA, Vendruscolo M. Sormanni P, et al. J Mol Biol. 2015 Jan 30;427(2):478-90. doi: 10.1016/j.jmb.2014.09.026. Epub 2014 Oct 14. J Mol Biol. 2015. PMID: 25451785

7

The s2D method: simultaneous sequence-based prediction of the statistical populations of ordered and disordered regions in proteins.

Sormanni P, Camilloni C, Fariselli P, Vendruscolo M. Sormanni P, et al. J Mol Biol. 2015 Feb 27;427(4):982-996. doi: 10.1016/j.jmb.2014.12.007. Epub 2014 Dec 20. J Mol Biol. 2015. PMID: 25534081

8

A Rational Design Strategy for the Selective Activity Enhancement of a Molecular Chaperone toward a Target Substrate.

Aprile FA, Sormanni P, Vendruscolo M. Aprile FA, et al. Among authors: sormanni p. Biochemistry. 2015 Aug 18;54(32):5103-12. doi: 10.1021/acs.biochem.5b00459. Epub 2015 Aug 7. Biochemistry. 2015. PMID: 26192230

9

Rational design of antibodies targeting specific epitopes within intrinsically disordered proteins.

Sormanni P, Aprile FA, Vendruscolo M. Sormanni P, et al. Proc Natl Acad Sci U S A. 2015 Aug 11;112(32):9902-7. doi: 10.1073/pnas.1422401112. Epub 2015 Jul 27. Proc Natl Acad Sci U S A. 2015. PMID: 26216991 Free PMC article.

10

Targeting disordered proteins with small molecules using entropy.

Heller GT, Sormanni P, Vendruscolo M. Heller GT, et al. Among authors: sormanni p. Trends Biochem Sci. 2015 Sep;40(9):491-6. doi: 10.1016/j.tibs.2015.07.004. Epub 2015 Aug 11. Trends Biochem Sci. 2015. PMID: 26275458 Review.

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