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Type I interferons and microbial metabolites of tryptophan modulate astrocyte activity and central nervous system inflammation via the aryl hydrocarbon receptor.
Rothhammer V, Mascanfroni ID, Bunse L, Takenaka MC, Kenison JE, Mayo L, Chao CC, Patel B, Yan R, Blain M, Alvarez JI, Kébir H, Anandasabapathy N, Izquierdo G, Jung S, Obholzer N, Pochet N, Clish CB, Prinz M, Prat A, Antel J, Quintana FJ. Rothhammer V, et al. Among authors: kebir h. Nat Med. 2016 Jun;22(6):586-97. doi: 10.1038/nm.4106. Epub 2016 May 9. Nat Med. 2016. PMID: 27158906 Free PMC article.
The Hedgehog pathway promotes blood-brain barrier integrity and CNS immune quiescence.
Alvarez JI, Dodelet-Devillers A, Kebir H, Ifergan I, Fabre PJ, Terouz S, Sabbagh M, Wosik K, Bourbonnière L, Bernard M, van Horssen J, de Vries HE, Charron F, Prat A. Alvarez JI, et al. Among authors: kebir h. Science. 2011 Dec 23;334(6063):1727-31. doi: 10.1126/science.1206936. Epub 2011 Dec 1. Science. 2011. PMID: 22144466
Melanoma cell adhesion molecule identifies encephalitogenic T lymphocytes and promotes their recruitment to the central nervous system.
Larochelle C, Cayrol R, Kebir H, Alvarez JI, Lécuyer MA, Ifergan I, Viel É, Bourbonnière L, Beauseigle D, Terouz S, Hachehouche L, Gendron S, Poirier J, Jobin C, Duquette P, Flanagan K, Yednock T, Arbour N, Prat A. Larochelle C, et al. Among authors: kebir h. Brain. 2012 Oct;135(Pt 10):2906-24. doi: 10.1093/brain/aws212. Epub 2012 Sep 13. Brain. 2012. PMID: 22975388
46 results