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Modulation of Alzheimer-like synaptic and cholinergic deficits in transgenic mice by human apolipoprotein E depends on isoform, aging, and overexpression of amyloid beta peptides but not on plaque formation.
Buttini M, Yu GQ, Shockley K, Huang Y, Jones B, Masliah E, Mallory M, Yeo T, Longo FM, Mucke L. Buttini M, et al. Among authors: huang y. J Neurosci. 2002 Dec 15;22(24):10539-48. doi: 10.1523/JNEUROSCI.22-24-10539.2002. J Neurosci. 2002. PMID: 12486146 Free PMC article.
Carboxyl-terminal-truncated apolipoprotein E4 causes Alzheimer's disease-like neurodegeneration and behavioral deficits in transgenic mice.
Harris FM, Brecht WJ, Xu Q, Tesseur I, Kekonius L, Wyss-Coray T, Fish JD, Masliah E, Hopkins PC, Scearce-Levie K, Weisgraber KH, Mucke L, Mahley RW, Huang Y. Harris FM, et al. Among authors: huang y. Proc Natl Acad Sci U S A. 2003 Sep 16;100(19):10966-71. doi: 10.1073/pnas.1434398100. Epub 2003 Aug 25. Proc Natl Acad Sci U S A. 2003. PMID: 12939405 Free PMC article.
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