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Mutations in mouse Aspm (abnormal spindle-like microcephaly associated) cause not only microcephaly but also major defects in the germline.
Pulvers JN, Bryk J, Fish JL, Wilsch-Bräuninger M, Arai Y, Schreier D, Naumann R, Helppi J, Habermann B, Vogt J, Nitsch R, Tóth A, Enard W, Pääbo S, Huttner WB. Pulvers JN, et al. Among authors: toth a. Proc Natl Acad Sci U S A. 2010 Sep 21;107(38):16595-600. doi: 10.1073/pnas.1010494107. Epub 2010 Sep 7. Proc Natl Acad Sci U S A. 2010. PMID: 20823249 Free PMC article.
Strong artificial selection in domestic mammals did not result in an increased recombination rate.
Muñoz-Fuentes V, Marcet-Ortega M, Alkorta-Aranburu G, Linde Forsberg C, Morrell JM, Manzano-Piedras E, Söderberg A, Daniel K, Villalba A, Toth A, Di Rienzo A, Roig I, Vilà C. Muñoz-Fuentes V, et al. Among authors: toth a. Mol Biol Evol. 2015 Feb;32(2):510-23. doi: 10.1093/molbev/msu322. Epub 2014 Nov 19. Mol Biol Evol. 2015. PMID: 25414125 Free PMC article.
1,481 results