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Early Antibody Lineage Diversification and Independent Limb Maturation Lead to Broad HIV-1 Neutralization Targeting the Env High-Mannose Patch.
MacLeod DT, Choi NM, Briney B, Garces F, Ver LS, Landais E, Murrell B, Wrin T, Kilembe W, Liang CH, Ramos A, Bian CB, Wickramasinghe L, Kong L, Eren K, Wu CY, Wong CH; IAVI Protocol C Investigators & The IAVI African HIV Research Network; Kosakovsky Pond SL, Wilson IA, Burton DR, Poignard P. MacLeod DT, et al. Among authors: kosakovsky pond sl. Immunity. 2016 May 17;44(5):1215-26. doi: 10.1016/j.immuni.2016.04.016. Immunity. 2016. PMID: 27192579 Free PMC article.
Neutralizing antibody responses drive the evolution of human immunodeficiency virus type 1 envelope during recent HIV infection.
Frost SD, Wrin T, Smith DM, Kosakovsky Pond SL, Liu Y, Paxinos E, Chappey C, Galovich J, Beauchaine J, Petropoulos CJ, Little SJ, Richman DD. Frost SD, et al. Among authors: kosakovsky pond sl. Proc Natl Acad Sci U S A. 2005 Dec 20;102(51):18514-9. doi: 10.1073/pnas.0504658102. Epub 2005 Dec 9. Proc Natl Acad Sci U S A. 2005. PMID: 16339909 Free PMC article.
Identification of an HIV-1 clade A envelope that exhibits broad antigenicity and neutralization sensitivity and elicits antibodies targeting three distinct epitopes.
Hoffenberg S, Powell R, Carpov A, Wagner D, Wilson A, Kosakovsky Pond S, Lindsay R, Arendt H, Destefano J, Phogat S, Poignard P, Fling SP, Simek M, Labranche C, Montefiori D, Wrin T, Phung P, Burton D, Koff W, King CR, Parks CL, Caulfield MJ. Hoffenberg S, et al. J Virol. 2013 May;87(10):5372-83. doi: 10.1128/JVI.02827-12. Epub 2013 Mar 6. J Virol. 2013. PMID: 23468492 Free PMC article.
IDEPI: rapid prediction of HIV-1 antibody epitopes and other phenotypic features from sequence data using a flexible machine learning platform.
Hepler NL, Scheffler K, Weaver S, Murrell B, Richman DD, Burton DR, Poignard P, Smith DM, Kosakovsky Pond SL. Hepler NL, et al. Among authors: kosakovsky pond sl. PLoS Comput Biol. 2014 Sep 25;10(9):e1003842. doi: 10.1371/journal.pcbi.1003842. eCollection 2014 Sep. PLoS Comput Biol. 2014. PMID: 25254639 Free PMC article.
RELAX: detecting relaxed selection in a phylogenetic framework.
Wertheim JO, Murrell B, Smith MD, Kosakovsky Pond SL, Scheffler K. Wertheim JO, et al. Among authors: kosakovsky pond sl. Mol Biol Evol. 2015 Mar;32(3):820-32. doi: 10.1093/molbev/msu400. Epub 2014 Dec 23. Mol Biol Evol. 2015. PMID: 25540451 Free PMC article.
160 results