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A single point in protein trafficking by Plasmodium falciparum determines the expression of major antigens on the surface of infected erythrocytes targeted by human antibodies.
Chan JA, Howell KB, Langer C, Maier AG, Hasang W, Rogerson SJ, Petter M, Chesson J, Stanisic DI, Duffy MF, Cooke BM, Siba PM, Mueller I, Bull PC, Marsh K, Fowkes FJ, Beeson JG. Chan JA, et al. Among authors: langer c. Cell Mol Life Sci. 2016 Nov;73(21):4141-58. doi: 10.1007/s00018-016-2267-1. Epub 2016 May 19. Cell Mol Life Sci. 2016. PMID: 27193441 Free PMC article.
IgM in human immunity to Plasmodium falciparum malaria.
Boyle MJ, Chan JA, Handayuni I, Reiling L, Feng G, Hilton A, Kurtovic L, Oyong D, Piera KA, Barber BE, William T, Eisen DP, Minigo G, Langer C, Drew DR, de Labastida Rivera F, Amante FH, Williams TN, Kinyanjui S, Marsh K, Doolan DL, Engwerda C, Fowkes FJI, Grigg MJ, Mueller I, McCarthy JS, Anstey NM, Beeson JG. Boyle MJ, et al. Among authors: langer c. Sci Adv. 2019 Sep 25;5(9):eaax4489. doi: 10.1126/sciadv.aax4489. eCollection 2019 Sep. Sci Adv. 2019. PMID: 31579826 Free PMC article.
Targets of antibodies against Plasmodium falciparum-infected erythrocytes in malaria immunity.
Chan JA, Howell KB, Reiling L, Ataide R, Mackintosh CL, Fowkes FJ, Petter M, Chesson JM, Langer C, Warimwe GM, Duffy MF, Rogerson SJ, Bull PC, Cowman AF, Marsh K, Beeson JG. Chan JA, et al. Among authors: langer c. J Clin Invest. 2012 Sep;122(9):3227-38. doi: 10.1172/JCI62182. Epub 2012 Aug 1. J Clin Invest. 2012. PMID: 22850879 Free PMC article.
The Plasmodium falciparum erythrocyte invasion ligand Pfrh4 as a target of functional and protective human antibodies against malaria.
Reiling L, Richards JS, Fowkes FJ, Wilson DW, Chokejindachai W, Barry AE, Tham WH, Stubbs J, Langer C, Donelson J, Michon P, Tavul L, Crabb BS, Siba PM, Cowman AF, Mueller I, Beeson JG. Reiling L, et al. Among authors: langer c. PLoS One. 2012;7(9):e45253. doi: 10.1371/journal.pone.0045253. Epub 2012 Sep 20. PLoS One. 2012. PMID: 23028883 Free PMC article.
Identification and prioritization of merozoite antigens as targets of protective human immunity to Plasmodium falciparum malaria for vaccine and biomarker development.
Richards JS, Arumugam TU, Reiling L, Healer J, Hodder AN, Fowkes FJ, Cross N, Langer C, Takeo S, Uboldi AD, Thompson JK, Gilson PR, Coppel RL, Siba PM, King CL, Torii M, Chitnis CE, Narum DL, Mueller I, Crabb BS, Cowman AF, Tsuboi T, Beeson JG. Richards JS, et al. Among authors: langer c. J Immunol. 2013 Jul 15;191(2):795-809. doi: 10.4049/jimmunol.1300778. Epub 2013 Jun 17. J Immunol. 2013. PMID: 23776179 Free PMC article.
Human antibodies fix complement to inhibit Plasmodium falciparum invasion of erythrocytes and are associated with protection against malaria.
Boyle MJ, Reiling L, Feng G, Langer C, Osier FH, Aspeling-Jones H, Cheng YS, Stubbs J, Tetteh KK, Conway DJ, McCarthy JS, Muller I, Marsh K, Anders RF, Beeson JG. Boyle MJ, et al. Among authors: langer c. Immunity. 2015 Mar 17;42(3):580-90. doi: 10.1016/j.immuni.2015.02.012. Immunity. 2015. PMID: 25786180 Free PMC article. Clinical Trial.
887 results