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Full ablation of C9orf72 in mice causes immune system-related pathology and neoplastic events but no motor neuron defects.
Sudria-Lopez E, Koppers M, de Wit M, van der Meer C, Westeneng HJ, Zundel CA, Youssef SA, Harkema L, de Bruin A, Veldink JH, van den Berg LH, Pasterkamp RJ. Sudria-Lopez E, et al. Among authors: de wit m, de bruin a. Acta Neuropathol. 2016 Jul;132(1):145-7. doi: 10.1007/s00401-016-1581-x. Epub 2016 May 20. Acta Neuropathol. 2016. PMID: 27206760 Free PMC article. No abstract available.
The progeroid phenotype of Ku80 deficiency is dominant over DNA-PKCS deficiency.
Reiling E, Dollé ME, Youssef SA, Lee M, Nagarajah B, Roodbergen M, de With P, de Bruin A, Hoeijmakers JH, Vijg J, van Steeg H, Hasty P. Reiling E, et al. Among authors: de with p, de bruin a. PLoS One. 2014 Apr 16;9(4):e93568. doi: 10.1371/journal.pone.0093568. eCollection 2014. PLoS One. 2014. PMID: 24740260 Free PMC article.
Chemokine-like receptor 1 deficiency does not affect the development of insulin resistance and nonalcoholic fatty liver disease in mice.
Gruben N, Aparicio Vergara M, Kloosterhuis NJ, van der Molen H, Stoelwinder S, Youssef S, de Bruin A, Delsing DJ, Kuivenhoven JA, van de Sluis B, Hofker MH, Koonen DP. Gruben N, et al. Among authors: de bruin a. PLoS One. 2014 Apr 29;9(4):e96345. doi: 10.1371/journal.pone.0096345. eCollection 2014. PLoS One. 2014. PMID: 24781986 Free PMC article.
Modeling tuberculous meningitis in zebrafish using Mycobacterium marinum.
van Leeuwen LM, van der Kuip M, Youssef SA, de Bruin A, Bitter W, van Furth AM, van der Sar AM. van Leeuwen LM, et al. Among authors: de bruin a. Dis Model Mech. 2014 Sep;7(9):1111-22. doi: 10.1242/dmm.015453. Epub 2014 Jul 4. Dis Model Mech. 2014. PMID: 24997190 Free PMC article.
A cell-type-specific role for murine Commd1 in liver inflammation.
Bartuzi P, Wijshake T, Dekker DC, Fedoseienko A, Kloosterhuis NJ, Youssef SA, Li H, Shiri-Sverdlov R, Kuivenhoven JA, de Bruin A, Burstein E, Hofker MH, van de Sluis B. Bartuzi P, et al. Among authors: de bruin a. Biochim Biophys Acta. 2014 Nov;1842(11):2257-65. doi: 10.1016/j.bbadis.2014.06.035. Epub 2014 Jul 27. Biochim Biophys Acta. 2014. PMID: 25072958 Free PMC article.
An essential role for senescent cells in optimal wound healing through secretion of PDGF-AA.
Demaria M, Ohtani N, Youssef SA, Rodier F, Toussaint W, Mitchell JR, Laberge RM, Vijg J, Van Steeg H, Dollé ME, Hoeijmakers JH, de Bruin A, Hara E, Campisi J. Demaria M, et al. Among authors: de bruin a. Dev Cell. 2014 Dec 22;31(6):722-33. doi: 10.1016/j.devcel.2014.11.012. Epub 2014 Dec 11. Dev Cell. 2014. PMID: 25499914 Free PMC article.
Lack of major genome instability in tumors of p53 null rats.
Hermsen R, Toonen P, Kuijk E, Youssef SA, Kuiper R, van Heesch S, de Bruin A, Cuppen E, Simonis M. Hermsen R, et al. Among authors: de bruin a. PLoS One. 2015 Mar 26;10(3):e0122066. doi: 10.1371/journal.pone.0122066. eCollection 2015. PLoS One. 2015. PMID: 25811670 Free PMC article.
392 results