Overk C - Search Results

1

Neuroprotective effects of the immunomodulatory drug FK506 in a model of HIV1-gp120 neurotoxicity.

Fields JA, Overk C, Adame A, Florio J, Mante M, Pineda A, Desplats P, Rockenstein E, Achim C, Masliah E. Fields JA, et al. Among authors: overk c. J Neuroinflammation. 2016 May 24;13(1):120. doi: 10.1186/s12974-016-0585-8. J Neuroinflammation. 2016. PMID: 27220536 Free PMC article.

2

The many faces of α-synuclein: from structure and toxicity to therapeutic target.

Lashuel HA, Overk CR, Oueslati A, Masliah E. Lashuel HA, et al. Nat Rev Neurosci. 2013 Jan;14(1):38-48. doi: 10.1038/nrn3406. Nat Rev Neurosci. 2013. PMID: 23254192 Free PMC article. Review.

3

Structural diversity of Alzheimer's disease amyloid-β dimers and their role in oligomerization and fibril formation.

Tsigelny IF, Sharikov Y, Kouznetsova VL, Greenberg JP, Wrasidlo W, Gonzalez T, Desplats P, Michael SE, Trejo-Morales M, Overk CR, Masliah E. Tsigelny IF, et al. J Alzheimers Dis. 2014;39(3):583-600. doi: 10.3233/JAD-131589. J Alzheimers Dis. 2014. PMID: 24240640 Free PMC article.

4

Pathogenesis of synaptic degeneration in Alzheimer's disease and Lewy body disease.

Overk CR, Masliah E. Overk CR, et al. Biochem Pharmacol. 2014 Apr 15;88(4):508-16. doi: 10.1016/j.bcp.2014.01.015. Epub 2014 Jan 21. Biochem Pharmacol. 2014. PMID: 24462903 Free PMC article. Review.

5

Environmental neurotoxic challenge of conditional alpha-synuclein transgenic mice predicts a dopaminergic olfactory-striatal interplay in early PD.

Nuber S, Tadros D, Fields J, Overk CR, Ettle B, Kosberg K, Mante M, Rockenstein E, Trejo M, Masliah E. Nuber S, et al. Acta Neuropathol. 2014 Apr;127(4):477-94. doi: 10.1007/s00401-014-1255-5. Epub 2014 Feb 8. Acta Neuropathol. 2014. PMID: 24509835 Free PMC article.

6

Accumulation of oligomer-prone α-synuclein exacerbates synaptic and neuronal degeneration in vivo.

Rockenstein E, Nuber S, Overk CR, Ubhi K, Mante M, Patrick C, Adame A, Trejo-Morales M, Gerez J, Picotti P, Jensen PH, Campioni S, Riek R, Winkler J, Gage FH, Winner B, Masliah E. Rockenstein E, et al. Among authors: overk cr. Brain. 2014 May;137(Pt 5):1496-513. doi: 10.1093/brain/awu057. Epub 2014 Mar 24. Brain. 2014. PMID: 24662516 Free PMC article.

7

Hippocampal neuronal cells that accumulate α-synuclein fragments are more vulnerable to Aβ oligomer toxicity via mGluR5--implications for dementia with Lewy bodies.

Overk CR, Cartier A, Shaked G, Rockenstein E, Ubhi K, Spencer B, Price DL, Patrick C, Desplats P, Masliah E. Overk CR, et al. Mol Neurodegener. 2014 May 19;9:18. doi: 10.1186/1750-1326-9-18. Mol Neurodegener. 2014. PMID: 24885390 Free PMC article.

8

Neuroprotective effects of the anti-cancer drug sunitinib in models of HIV neurotoxicity suggests potential for the treatment of neurodegenerative disorders.

Wrasidlo W, Crews LA, Tsigelny IF, Stocking E, Kouznetsova VL, Price D, Paulino A, Gonzales T, Overk CR, Patrick C, Rockenstein E, Masliah E. Wrasidlo W, et al. Among authors: overk cr. Br J Pharmacol. 2014 Dec;171(24):5757-73. doi: 10.1111/bph.12875. Br J Pharmacol. 2014. PMID: 25117211 Free PMC article.

9

Toward a unified therapeutics approach targeting putative amyloid-β oligomer receptors.

Overk CR, Masliah E. Overk CR, et al. Proc Natl Acad Sci U S A. 2014 Sep 23;111(38):13680-1. doi: 10.1073/pnas.1414554111. Epub 2014 Sep 9. Proc Natl Acad Sci U S A. 2014. PMID: 25205809 Free PMC article. No abstract available.

10

Molecular determinants of α-synuclein mutants' oligomerization and membrane interactions.

Tsigelny IF, Sharikov Y, Kouznetsova VL, Greenberg JP, Wrasidlo W, Overk C, Gonzalez T, Trejo M, Spencer B, Kosberg K, Masliah E. Tsigelny IF, et al. Among authors: overk c. ACS Chem Neurosci. 2015 Mar 18;6(3):403-16. doi: 10.1021/cn500332w. Epub 2015 Jan 21. ACS Chem Neurosci. 2015. PMID: 25561023 Free PMC article.

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