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Exploring the structure-activity relationship of benzylidene-2,3-dihydro-1H-inden-1-one compared to benzofuran-3(2H)-one derivatives as inhibitors of tau amyloid fibers.
Boukherrouba E, Larosa C, Nguyen KA, Caburet J, Lunven L, Bonnet H, Fortuné A, Boumendjel A, Boucherle B, Chierici S, Peuchmaur M. Boukherrouba E, et al. Among authors: lunven l. Eur J Med Chem. 2022 Mar 5;231:114139. doi: 10.1016/j.ejmech.2022.114139. Epub 2022 Jan 21. Eur J Med Chem. 2022. PMID: 35101652
Modulation of macrophage inflammatory function through selective inhibition of the epigenetic reader protein SP140.
Ghiboub M, Koster J, Craggs PD, Li Yim AYF, Shillings A, Hutchinson S, Bingham RP, Gatfield K, Hageman IL, Yao G, O'Keefe HP, Coffin A, Patel A, Sloan LA, Mitchell DJ, Hayhow TG, Lunven L, Watson RJ, Blunt CE, Harrison LA, Bruton G, Kumar U, Hamer N, Spaull JR, Zwijnenburg DA, Welting O, Hakvoort TBM, Te Velde AA, van Limbergen J, Henneman P, Prinjha RK, de Winther MPJ, Harker NR, Tough DF, de Jonge WJ. Ghiboub M, et al. Among authors: lunven l. BMC Biol. 2022 Aug 19;20(1):182. doi: 10.1186/s12915-022-01380-6. BMC Biol. 2022. PMID: 35986286 Free PMC article.