Smith MJ - Search Results

1

Biochemical Classification of Disease-associated Mutants of RAS-like Protein Expressed in Many Tissues (RIT1).

Fang Z, Marshall CB, Yin JC, Mazhab-Jafari MT, Gasmi-Seabrook GM, Smith MJ, Nishikawa T, Xu Y, Neel BG, Ikura M. Fang Z, et al. Among authors: smith mj. J Biol Chem. 2016 Jul 22;291(30):15641-52. doi: 10.1074/jbc.M116.714196. Epub 2016 May 18. J Biol Chem. 2016. PMID: 27226556 Free PMC article.

2

Real-time NMR study of three small GTPases reveals that fluorescent 2'(3')-O-(N-methylanthraniloyl)-tagged nucleotides alter hydrolysis and exchange kinetics.

Mazhab-Jafari MT, Marshall CB, Smith M, Gasmi-Seabrook GM, Stambolic V, Rottapel R, Neel BG, Ikura M. Mazhab-Jafari MT, et al. J Biol Chem. 2010 Feb 19;285(8):5132-6. doi: 10.1074/jbc.C109.064766. Epub 2009 Dec 14. J Biol Chem. 2010. PMID: 20018863 Free PMC article.

3

The PTB domain of ShcA couples receptor activation to the cytoskeletal regulator IQGAP1.

Smith MJ, Hardy WR, Li GY, Goudreault M, Hersch S, Metalnikov P, Starostine A, Pawson T, Ikura M. Smith MJ, et al. EMBO J. 2010 Mar 3;29(5):884-96. doi: 10.1038/emboj.2009.399. Epub 2010 Jan 14. EMBO J. 2010. PMID: 20075861 Free PMC article.

4

Dynamic and static interactions between p120 catenin and E-cadherin regulate the stability of cell-cell adhesion.

Ishiyama N, Lee SH, Liu S, Li GY, Smith MJ, Reichardt LF, Ikura M. Ishiyama N, et al. Among authors: smith mj. Cell. 2010 Apr 2;141(1):117-28. doi: 10.1016/j.cell.2010.01.017. Cell. 2010. PMID: 20371349 Free article.

5

Probing the GTPase cycle with real-time NMR: GAP and GEF activities in cell extracts.

Marshall CB, Meiri D, Smith MJ, Mazhab-Jafari MT, Gasmi-Seabrook GM, Rottapel R, Stambolic V, Ikura M. Marshall CB, et al. Among authors: smith mj. Methods. 2012 Aug;57(4):473-85. doi: 10.1016/j.ymeth.2012.06.014. Epub 2012 Jun 28. Methods. 2012. PMID: 22750304

6

Interaction domains of Sos1/Grb2 are finely tuned for cooperative control of embryonic stem cell fate.

Findlay GM, Smith MJ, Lanner F, Hsiung MS, Gish GD, Petsalaki E, Cockburn K, Kaneko T, Huang H, Bagshaw RD, Ketela T, Tucholska M, Taylor L, Bowtell DD, Moffat J, Ikura M, Li SS, Sidhu SS, Rossant J, Pawson T. Findlay GM, et al. Among authors: smith mj. Cell. 2013 Feb 28;152(5):1008-20. doi: 10.1016/j.cell.2013.01.056. Cell. 2013. PMID: 23452850 Free article.

7

NMR-based functional profiling of RASopathies and oncogenic RAS mutations.

Smith MJ, Neel BG, Ikura M. Smith MJ, et al. Proc Natl Acad Sci U S A. 2013 Mar 19;110(12):4574-9. doi: 10.1073/pnas.1218173110. Epub 2013 Mar 4. Proc Natl Acad Sci U S A. 2013. PMID: 23487764 Free PMC article.

8

A comparative CEST NMR study of slow conformational dynamics of small GTPases complexed with GTP and GTP analogues.

Long D, Marshall CB, Bouvignies G, Mazhab-Jafari MT, Smith MJ, Ikura M, Kay LE. Long D, et al. Among authors: smith mj. Angew Chem Int Ed Engl. 2013 Oct 4;52(41):10771-4. doi: 10.1002/anie.201305434. Epub 2013 Aug 22. Angew Chem Int Ed Engl. 2013. PMID: 24039022 No abstract available.

9

Integrated RAS signaling defined by parallel NMR detection of effectors and regulators.

Smith MJ, Ikura M. Smith MJ, et al. Nat Chem Biol. 2014 Mar;10(3):223-30. doi: 10.1038/nchembio.1435. Epub 2014 Jan 19. Nat Chem Biol. 2014. PMID: 24441586

10

Real-time NMR monitoring of biological activities in complex physiological environments.

Smith MJ, Marshall CB, Theillet FX, Binolfi A, Selenko P, Ikura M. Smith MJ, et al. Curr Opin Struct Biol. 2015 Jun;32:39-47. doi: 10.1016/j.sbi.2015.02.003. Epub 2015 Feb 27. Curr Opin Struct Biol. 2015. PMID: 25727665 Review.

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