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Synthesis and chemical and biological comparison of nitroxyl- and nitric oxide-releasing diazeniumdiolate-based aspirin derivatives.
Basudhar D, Bharadwaj G, Cheng RY, Jain S, Shi S, Heinecke JL, Holland RJ, Ridnour LA, Caceres VM, Spadari-Bratfisch RC, Paolocci N, Velázquez-Martínez CA, Wink DA, Miranda KM. Basudhar D, et al. J Med Chem. 2013 Oct 24;56(20):7804-20. doi: 10.1021/jm400196q. Epub 2013 Oct 8. J Med Chem. 2013. PMID: 24102516 Free PMC article.
Comparing the chemical biology of NO and HNO.
Flores-Santana W, Switzer C, Ridnour LA, Basudhar D, Mancardi D, Donzelli S, Thomas DD, Miranda KM, Fukuto JM, Wink DA. Flores-Santana W, et al. Among authors: basudhar d. Arch Pharm Res. 2009 Aug;32(8):1139-53. doi: 10.1007/s12272-009-1805-x. Epub 2009 Aug 29. Arch Pharm Res. 2009. PMID: 19727606
The emergence of nitroxyl (HNO) as a pharmacological agent.
Switzer CH, Flores-Santana W, Mancardi D, Donzelli S, Basudhar D, Ridnour LA, Miranda KM, Fukuto JM, Paolocci N, Wink DA. Switzer CH, et al. Among authors: basudhar d. Biochim Biophys Acta. 2009 Jul;1787(7):835-40. doi: 10.1016/j.bbabio.2009.04.015. Epub 2009 May 6. Biochim Biophys Acta. 2009. PMID: 19426703 Free PMC article. Review.
The specificity of nitroxyl chemistry is unique among nitrogen oxides in biological systems.
Flores-Santana W, Salmon DJ, Donzelli S, Switzer CH, Basudhar D, Ridnour L, Cheng R, Glynn SA, Paolocci N, Fukuto JM, Miranda KM, Wink DA. Flores-Santana W, et al. Among authors: basudhar d. Antioxid Redox Signal. 2011 May 1;14(9):1659-74. doi: 10.1089/ars.2010.3841. Epub 2011 Mar 16. Antioxid Redox Signal. 2011. PMID: 21235346 Free PMC article. Review.
21 results