Sliwkowski MX - Search Results

1

HER2-Targeted Polyinosine/Polycytosine Therapy Inhibits Tumor Growth and Modulates the Tumor Immune Microenvironment.

Zigler M, Shir A, Joubran S, Sagalov A, Klein S, Edinger N, Lau J, Yu SF, Mizraji G, Globerson Levin A, Sliwkowski MX, Levitzki A. Zigler M, et al. Among authors: sliwkowski mx. Cancer Immunol Res. 2016 Aug;4(8):688-97. doi: 10.1158/2326-6066.CIR-15-0203. Epub 2016 May 30. Cancer Immunol Res. 2016. PMID: 27241844

2

A central role for HER3 in HER2-amplified breast cancer: implications for targeted therapy.

Lee-Hoeflich ST, Crocker L, Yao E, Pham T, Munroe X, Hoeflich KP, Sliwkowski MX, Stern HM. Lee-Hoeflich ST, et al. Among authors: sliwkowski mx. Cancer Res. 2008 Jul 15;68(14):5878-87. doi: 10.1158/0008-5472.CAN-08-0380. Cancer Res. 2008. PMID: 18632642

3

Targeting HER2-positive breast cancer with trastuzumab-DM1, an antibody-cytotoxic drug conjugate.

Lewis Phillips GD, Li G, Dugger DL, Crocker LM, Parsons KL, Mai E, Blättler WA, Lambert JM, Chari RV, Lutz RJ, Wong WL, Jacobson FS, Koeppen H, Schwall RH, Kenkare-Mitra SR, Spencer SD, Sliwkowski MX. Lewis Phillips GD, et al. Among authors: sliwkowski mx. Cancer Res. 2008 Nov 15;68(22):9280-90. doi: 10.1158/0008-5472.CAN-08-1776. Cancer Res. 2008. PMID: 19010901

4

Superior in vivo efficacy of afucosylated trastuzumab in the treatment of HER2-amplified breast cancer.

Junttila TT, Parsons K, Olsson C, Lu Y, Xin Y, Theriault J, Crocker L, Pabonan O, Baginski T, Meng G, Totpal K, Kelley RF, Sliwkowski MX. Junttila TT, et al. Among authors: sliwkowski mx. Cancer Res. 2010 Jun 1;70(11):4481-9. doi: 10.1158/0008-5472.CAN-09-3704. Epub 2010 May 18. Cancer Res. 2010. PMID: 20484044

5

Suppression of HER2/HER3-mediated growth of breast cancer cells with combinations of GDC-0941 PI3K inhibitor, trastuzumab, and pertuzumab.

Yao E, Zhou W, Lee-Hoeflich ST, Truong T, Haverty PM, Eastham-Anderson J, Lewin-Koh N, Gunter B, Belvin M, Murray LJ, Friedman LS, Sliwkowski MX, Hoeflich KP. Yao E, et al. Among authors: sliwkowski mx. Clin Cancer Res. 2009 Jun 15;15(12):4147-56. doi: 10.1158/1078-0432.CCR-08-2814. Epub 2009 Jun 9. Clin Cancer Res. 2009. PMID: 19509167

6

Kinetic analysis of epidermal growth factor receptor somatic mutant proteins shows increased sensitivity to the epidermal growth factor receptor tyrosine kinase inhibitor, erlotinib.

Carey KD, Garton AJ, Romero MS, Kahler J, Thomson S, Ross S, Park F, Haley JD, Gibson N, Sliwkowski MX. Carey KD, et al. Among authors: sliwkowski mx. Cancer Res. 2006 Aug 15;66(16):8163-71. doi: 10.1158/0008-5472.CAN-06-0453. Cancer Res. 2006. PMID: 16912195

7

Toward an effective targeted chemotherapy for multiple myeloma.

Polson AG, Sliwkowski MX. Polson AG, et al. Among authors: sliwkowski mx. Clin Cancer Res. 2009 Jun 15;15(12):3906-7. doi: 10.1158/1078-0432.CCR-09-0572. Epub 2009 Jun 9. Clin Cancer Res. 2009. PMID: 19509145

8

Growth regulation of human breast and ovarian tumor cells by heregulin: Evidence for the requirement of ErbB2 as a critical component in mediating heregulin responsiveness.

Lewis GD, Lofgren JA, McMurtrey AE, Nuijens A, Fendly BM, Bauer KD, Sliwkowski MX. Lewis GD, et al. Among authors: sliwkowski mx. Cancer Res. 1996 Mar 15;56(6):1457-65. Cancer Res. 1996. PMID: 8640840

9

Ligand-independent HER2/HER3/PI3K complex is disrupted by trastuzumab and is effectively inhibited by the PI3K inhibitor GDC-0941.

Junttila TT, Akita RW, Parsons K, Fields C, Lewis Phillips GD, Friedman LS, Sampath D, Sliwkowski MX. Junttila TT, et al. Among authors: sliwkowski mx. Cancer Cell. 2009 May 5;15(5):429-40. doi: 10.1016/j.ccr.2009.03.020. Cancer Cell. 2009. PMID: 19411071 Free article.

10

Trastuzumab-DM1 (T-DM1) retains all the mechanisms of action of trastuzumab and efficiently inhibits growth of lapatinib insensitive breast cancer.

Junttila TT, Li G, Parsons K, Phillips GL, Sliwkowski MX. Junttila TT, et al. Among authors: sliwkowski mx. Breast Cancer Res Treat. 2011 Jul;128(2):347-56. doi: 10.1007/s10549-010-1090-x. Epub 2010 Aug 21. Breast Cancer Res Treat. 2011. PMID: 20730488

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