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Loss of p300 accelerates MDS-associated leukemogenesis.
Cheng G, Liu F, Asai T, Lai F, Man N, Xu H, Chen S, Greenblatt S, Hamard PJ, Ando K, Chen X, Wang L, Martinez C, Tadi M, Wang L, Xu M, Yang FC, Shiekhattar R, Nimer SD. Cheng G, et al. Among authors: man n. Leukemia. 2017 Jun;31(6):1382-1390. doi: 10.1038/leu.2016.347. Epub 2016 Nov 24. Leukemia. 2017. PMID: 27881875 Free PMC article.
TAF1 plays a critical role in AML1-ETO driven leukemogenesis.
Xu Y, Man N, Karl D, Martinez C, Liu F, Sun J, Martinez CJ, Martin GM, Beckedorff F, Lai F, Yue J, Roisman A, Greenblatt S, Duffort S, Wang L, Sun X, Figueroa M, Shiekhattar R, Nimer S. Xu Y, et al. Among authors: man n. Nat Commun. 2019 Oct 29;10(1):4925. doi: 10.1038/s41467-019-12735-z. Nat Commun. 2019. PMID: 31664040 Free PMC article.
Different roles of E proteins in t(8;21) leukemia: E2-2 compromises the function of AETFC and negatively regulates leukemogenesis.
Liu N, Song J, Xie Y, Wang XL, Rong B, Man N, Zhang MM, Zhang Q, Gao FF, Du MR, Zhang Y, Shen J, Xu CH, Hu CL, Wu JC, Liu P, Zhang YL, Xie YY, Liu P, Huang JY, Huang QH, Lan F, Shen S, Nimer SD, Chen Z, Chen SJ, Roeder RG, Wang L, Sun XJ. Liu N, et al. Among authors: man n. Proc Natl Acad Sci U S A. 2019 Jan 15;116(3):890-899. doi: 10.1073/pnas.1809327116. Epub 2018 Dec 28. Proc Natl Acad Sci U S A. 2019. PMID: 30593567 Free PMC article.
p300 suppresses the transition of myelodysplastic syndromes to acute myeloid leukemia.
Man N, Mas G, Karl DL, Sun J, Liu F, Yang Q, Torres-Martin M, Itonaga H, Martinez C, Chen S, Xu Y, Duffort S, Hamard PJ, Chen C, Zucconi BE, Cimmino L, Yang FC, Xu M, Cole PA, Figueroa ME, Nimer SD. Man N, et al. JCI Insight. 2021 Oct 8;6(19):e138478. doi: 10.1172/jci.insight.138478. JCI Insight. 2021. PMID: 34622806 Free PMC article.
353 results