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Incorporation of Phosphonate into Benzonaphthyridine Toll-like Receptor 7 Agonists for Adsorption to Aluminum Hydroxide.
Cortez A, Li Y, Miller AT, Zhang X, Yue K, Maginnis J, Hampton J, Hall de S, Shapiro M, Nayak B, D'Oro U, Li C, Skibinski D, Mbow ML, Singh M, O'Hagan DT, Cooke MP, Valiante NM, Wu TY. Cortez A, et al. Among authors: zhang x. J Med Chem. 2016 Jun 23;59(12):5868-78. doi: 10.1021/acs.jmedchem.6b00489. Epub 2016 Jun 13. J Med Chem. 2016. PMID: 27270029
Selective DYRK1A Inhibitor for the Treatment of Type 1 Diabetes: Discovery of 6-Azaindole Derivative GNF2133.
Liu YA, Jin Q, Zou Y, Ding Q, Yan S, Wang Z, Hao X, Nguyen B, Zhang X, Pan J, Mo T, Jacobsen K, Lam T, Wu TY, Petrassi HM, Bursulaya B, DiDonato M, Gordon WP, Liu B, Baaten J, Hill R, Nguyen-Tran V, Qiu M, Zhang YQ, Kamireddy A, Espinola S, Deaton L, Ha S, Harb G, Jia Y, Li J, Shen W, Schumacher AM, Colman K, Glynne R, Pan S, McNamara P, Laffitte B, Meeusen S, Molteni V, Loren J. Liu YA, et al. Among authors: zhang yq, zhang x. J Med Chem. 2020 Mar 26;63(6):2958-2973. doi: 10.1021/acs.jmedchem.9b01624. Epub 2020 Feb 20. J Med Chem. 2020. PMID: 32077280
A Dual Inhibitor of DYRK1A and GSK3β for β-Cell Proliferation: Aminopyrazine Derivative GNF4877.
Liu YA, Jin Q, Ding Q, Hao X, Mo T, Yan S, Zou Y, Huang Z, Zhang X, Gao W, Wu TY, Li C, Bursalaya B, Di Donato M, Zhang YQ, Deaton L, Shen W, Taylor B, Kamireddy A, Harb G, Li J, Jia Y, Schumacher AM, Laffitte B, Glynne R, Pan S, McNamara P, Molteni V, Loren J. Liu YA, et al. Among authors: zhang yq, zhang x. ChemMedChem. 2020 Aug 19;15(16):1562-1570. doi: 10.1002/cmdc.202000183. Epub 2020 Jul 2. ChemMedChem. 2020. PMID: 32613743
Global impacts of land use on terrestrial carbon emissions since 1850.
Yuan X, Bai X, Zhou Z, Luo G, Li J, Ran C, Zhang S, Xiong L, Liao J, Du C, Dai L, Li Z, Xue Y, Long M, Luo Q, Zhang X, Li M, Shen X, Yang S. Yuan X, et al. Among authors: zhang x. Sci Total Environ. 2025 Jan 15;963:178358. doi: 10.1016/j.scitotenv.2024.178358. Online ahead of print. Sci Total Environ. 2025. PMID: 39818149
Discovery of phloridzin as a new antagonist for Di(2-ethylhexyl) phthalate-induced male reproductive toxicity based on the adverse outcome pathway network and drug-target gene set enrichment analysis.
Gao H, Zhang X, Liu Z, Yang X, Li Y, Cui M, Wang H, Chen X, Zhang W, Liu Z, Yu Y, Chen L, Li D, Xiao Y, Chen W, Wang Q. Gao H, et al. Among authors: zhang x. Ecotoxicol Environ Saf. 2025 Jan 15;290:117740. doi: 10.1016/j.ecoenv.2025.117740. Online ahead of print. Ecotoxicol Environ Saf. 2025. PMID: 39818139
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