Nielsen EI - Search Results

1

Development and Evaluation of a Gentamicin Pharmacokinetic Model That Facilitates Opportunistic Gentamicin Therapeutic Drug Monitoring in Neonates and Infants.

Germovsek E, Kent A, Metsvaht T, Lutsar I, Klein N, Turner MA, Sharland M, Nielsen EI, Heath PT, Standing JF. Germovsek E, et al. Among authors: nielsen ei. Antimicrob Agents Chemother. 2016 Jul 22;60(8):4869-77. doi: 10.1128/AAC.00577-16. Print 2016 Aug. Antimicrob Agents Chemother. 2016. PMID: 27270281 Free PMC article.

2

Semimechanistic pharmacokinetic/pharmacodynamic model for assessment of activity of antibacterial agents from time-kill curve experiments.

Nielsen EI, Viberg A, Löwdin E, Cars O, Karlsson MO, Sandström M. Nielsen EI, et al. Antimicrob Agents Chemother. 2007 Jan;51(1):128-36. doi: 10.1128/AAC.00604-06. Epub 2006 Oct 23. Antimicrob Agents Chemother. 2007. PMID: 17060524 Free PMC article.

3

Developmental pharmacokinetics of gentamicin in preterm and term neonates: population modelling of a prospective study.

Nielsen EI, Sandström M, Honoré PH, Ewald U, Friberg LE. Nielsen EI, et al. Clin Pharmacokinet. 2009;48(4):253-63. doi: 10.2165/00003088-200948040-00003. Clin Pharmacokinet. 2009. PMID: 19492870 Clinical Trial.

4

Predicting in vitro antibacterial efficacy across experimental designs with a semimechanistic pharmacokinetic-pharmacodynamic model.

Nielsen EI, Cars O, Friberg LE. Nielsen EI, et al. Antimicrob Agents Chemother. 2011 Apr;55(4):1571-9. doi: 10.1128/AAC.01286-10. Epub 2011 Jan 31. Antimicrob Agents Chemother. 2011. PMID: 21282424 Free PMC article.

5

Pharmacokinetic/pharmacodynamic (PK/PD) indices of antibiotics predicted by a semimechanistic PKPD model: a step toward model-based dose optimization.

Nielsen EI, Cars O, Friberg LE. Nielsen EI, et al. Antimicrob Agents Chemother. 2011 Oct;55(10):4619-30. doi: 10.1128/AAC.00182-11. Epub 2011 Aug 1. Antimicrob Agents Chemother. 2011. PMID: 21807983 Free PMC article.

6

Pharmacokinetic-pharmacodynamic model for gentamicin and its adaptive resistance with predictions of dosing schedules in newborn infants.

Mohamed AF, Nielsen EI, Cars O, Friberg LE. Mohamed AF, et al. Among authors: nielsen ei. Antimicrob Agents Chemother. 2012 Jan;56(1):179-88. doi: 10.1128/AAC.00694-11. Epub 2011 Oct 28. Antimicrob Agents Chemother. 2012. PMID: 22037853 Free PMC article.

7

A mechanism-based pharmacokinetic/pharmacodynamic model allows prediction of antibiotic killing from MIC values for WT and mutants.

Khan DD, Lagerbäck P, Cao S, Lustig U, Nielsen EI, Cars O, Hughes D, Andersson DI, Friberg LE. Khan DD, et al. Among authors: nielsen ei. J Antimicrob Chemother. 2015 Nov;70(11):3051-60. doi: 10.1093/jac/dkv233. Epub 2015 Sep 7. J Antimicrob Chemother. 2015. PMID: 26349518

8

Dynamic interaction of colistin and meropenem on a WT and a resistant strain of Pseudomonas aeruginosa as quantified in a PK/PD model.

Mohamed AF, Kristoffersson AN, Karvanen M, Nielsen EI, Cars O, Friberg LE. Mohamed AF, et al. Among authors: nielsen ei. J Antimicrob Chemother. 2016 May;71(5):1279-90. doi: 10.1093/jac/dkv488. Epub 2016 Feb 4. J Antimicrob Chemother. 2016. PMID: 26850719

9

A pharmacokinetic-pharmacodynamic (PKPD) model based on in vitro time-kill data predicts the in vivo PK/PD index of colistin.

Khan DD, Friberg LE, Nielsen EI. Khan DD, et al. Among authors: nielsen ei. J Antimicrob Chemother. 2016 Jul;71(7):1881-4. doi: 10.1093/jac/dkw057. Epub 2016 Mar 16. J Antimicrob Chemother. 2016. PMID: 26983860

10

A pharmacokinetic-pharmacodynamic model characterizing the emergence of resistant Escherichia coli subpopulations during ertapenem exposure.

Ungphakorn W, Tängdén T, Sandegren L, Nielsen EI. Ungphakorn W, et al. Among authors: nielsen ei. J Antimicrob Chemother. 2016 Sep;71(9):2521-33. doi: 10.1093/jac/dkw205. Epub 2016 Jun 20. J Antimicrob Chemother. 2016. PMID: 27330073

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