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Inhibition of SOAT1 Suppresses Glioblastoma Growth via Blocking SREBP-1-Mediated Lipogenesis.
Geng F, Cheng X, Wu X, Yoo JY, Cheng C, Guo JY, Mo X, Ru P, Hurwitz B, Kim SH, Otero J, Puduvalli V, Lefai E, Ma J, Nakano I, Horbinski C, Kaur B, Chakravarti A, Guo D. Geng F, et al. Among authors: nakano i. Clin Cancer Res. 2016 Nov 1;22(21):5337-5348. doi: 10.1158/1078-0432.CCR-15-2973. Epub 2016 Jun 8. Clin Cancer Res. 2016. PMID: 27281560 Free PMC article.
Telomestatin impairs glioma stem cell survival and growth through the disruption of telomeric G-quadruplex and inhibition of the proto-oncogene, c-Myb.
Miyazaki T, Pan Y, Joshi K, Purohit D, Hu B, Demir H, Mazumder S, Okabe S, Yamori T, Viapiano M, Shin-ya K, Seimiya H, Nakano I. Miyazaki T, et al. Among authors: nakano i. Clin Cancer Res. 2012 Mar 1;18(5):1268-80. doi: 10.1158/1078-0432.CCR-11-1795. Epub 2012 Jan 9. Clin Cancer Res. 2012. PMID: 22230766 Free PMC article.
Impairment of glioma stem cell survival and growth by a novel inhibitor for Survivin-Ran protein complex.
Guvenc H, Pavlyukov MS, Joshi K, Kurt H, Banasavadi-Siddegowda YK, Mao P, Hong C, Yamada R, Kwon CH, Bhasin D, Chettiar S, Kitange G, Park IH, Sarkaria JN, Li C, Shakhparonov MI, Nakano I. Guvenc H, et al. Among authors: nakano i. Clin Cancer Res. 2013 Feb 1;19(3):631-42. doi: 10.1158/1078-0432.CCR-12-0647. Epub 2012 Dec 18. Clin Cancer Res. 2013. PMID: 23251006 Free PMC article.
Mesenchymal glioma stem cells are maintained by activated glycolytic metabolism involving aldehyde dehydrogenase 1A3.
Mao P, Joshi K, Li J, Kim SH, Li P, Santana-Santos L, Luthra S, Chandran UR, Benos PV, Smith L, Wang M, Hu B, Cheng SY, Sobol RW, Nakano I. Mao P, et al. Among authors: nakano i. Proc Natl Acad Sci U S A. 2013 May 21;110(21):8644-9. doi: 10.1073/pnas.1221478110. Epub 2013 May 6. Proc Natl Acad Sci U S A. 2013. PMID: 23650391 Free PMC article. Clinical Trial.
Extracellular vesicles modulate the glioblastoma microenvironment via a tumor suppression signaling network directed by miR-1.
Bronisz A, Wang Y, Nowicki MO, Peruzzi P, Ansari K, Ogawa D, Balaj L, De Rienzo G, Mineo M, Nakano I, Ostrowski MC, Hochberg F, Weissleder R, Lawler SE, Chiocca EA, Godlewski J. Bronisz A, et al. Among authors: nakano i. Cancer Res. 2014 Feb 1;74(3):738-750. doi: 10.1158/0008-5472.CAN-13-2650. Epub 2013 Dec 5. Cancer Res. 2014. PMID: 24310399 Free PMC article.
1,208 results