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Page 1
Evidence for the involvement of TNF-α and IL-1β in the antinociceptive and anti-inflammatory activity of Stachys lavandulifolia Vahl. (Lamiaceae) essential oil and (-)-α-bisabolol, its main compound, in mice.
Barreto RSS, Quintans JSS, Amarante RKL, Nascimento TS, Amarante RS, Barreto AS, Pereira EWM, Duarte MC, Coutinho HDM, Menezes IRA, Zengin G, Aktumsek A, Quintans-Júnior LJ. Barreto RSS, et al. Among authors: pereira ewm. J Ethnopharmacol. 2016 Sep 15;191:9-18. doi: 10.1016/j.jep.2016.06.022. Epub 2016 Jun 9. J Ethnopharmacol. 2016. PMID: 27292196
D-limonene exhibits superior antihyperalgesic effects in a β-cyclodextrin-complexed form in chronic musculoskeletal pain reducing Fos protein expression on spinal cord in mice.
Araújo-Filho HG, Pereira EWM, Rezende MM, Menezes PP, Araújo AAS, Barreto RSS, Martins AOBPB, Albuquerque TR, Silva BAF, Alcantara IS, Coutinho HDM, Menezes IRA, Quintans-Júnior LJ, Quintans JSS. Araújo-Filho HG, et al. Among authors: pereira ewm. Neuroscience. 2017 Sep 1;358:158-169. doi: 10.1016/j.neuroscience.2017.06.037. Epub 2017 Jul 1. Neuroscience. 2017. PMID: 28673718
Chronic orofacial pain animal models - progress and challenges.
Araújo-Filho HG, Pereira EWM, Campos AR, Quintans-Júnior LJ, Quintans JSS. Araújo-Filho HG, et al. Among authors: pereira ewm. Expert Opin Drug Discov. 2018 Oct;13(10):949-964. doi: 10.1080/17460441.2018.1524458. Epub 2018 Oct 4. Expert Opin Drug Discov. 2018. PMID: 30220225 Review.
Involvement of the PKA pathway and inhibition of voltage gated Ca2+ channels in antihyperalgesic activity of Lippia grata/β-cyclodextrin.
Siqueira-Lima PS, Quintans JSS, Heimfarth L, Passos FRS, Pereira EWM, Rezende MM, Menezes-Filho JER, Barreto RSS, Coutinho HDM, Araújo AAS, Medrado AS, Naves LA, Bomfim HF, Lucchese AM, Gandhi SR, Quintans-Júnior LJ. Siqueira-Lima PS, et al. Among authors: pereira ewm. Life Sci. 2019 Dec 15;239:116961. doi: 10.1016/j.lfs.2019.116961. Epub 2019 Oct 22. Life Sci. 2019. PMID: 31654745 Free article.
Limonene, a citrus monoterpene, non-complexed and complexed with hydroxypropyl-β-cyclodextrin attenuates acute and chronic orofacial nociception in rodents: Evidence for involvement of the PKA and PKC pathway.
Pereira EWM, Heimfarth L, Santos TK, Passos FRS, Siqueira-Lima P, Scotti L, Scotti MT, Almeida JRGDS, Campos AR, Coutinho HDM, Martin P, Quintans-Júnior LJ, Quintans JSS. Pereira EWM, et al. Phytomedicine. 2022 Feb;96:153893. doi: 10.1016/j.phymed.2021.153893. Epub 2021 Dec 18. Phytomedicine. 2022. PMID: 35026511
Inclusion complex between β-cyclodextrin and hecogenin acetate produces superior analgesic effect in animal models for orofacial pain.
Carvalho YMBG, Menezes PP, Sousa BMH, Lima BS, Trindade IAS, Serafini MR, Pereira EWM, Rezende MM, Quintans JSS, Quintans-Júnior LJ, Nakamura CV, Silva-Júnior EF, Crispim AC, Aquino TM, Araújo AAS. Carvalho YMBG, et al. Among authors: pereira ewm. Biomed Pharmacother. 2017 Sep;93:754-762. doi: 10.1016/j.biopha.2017.06.091. Epub 2017 Jul 10. Biomed Pharmacother. 2017. PMID: 28704800
Limonene, a food additive, and its active metabolite perillyl alcohol improve regeneration and attenuate neuropathic pain after peripheral nerve injury: Evidence for IL-1β, TNF-α, GAP, NGF and ERK involvement.
Araújo-Filho HG, Pereira EWM, Heimfarth L, Souza Monteiro B, Santos Passos FR, Siqueira-Lima P, Gandhi SR, Viana Dos Santos MR, Guedes da Silva Almeida JR, Picot L, Grougnet R, Almeida RS, Douglas Melo Coutinho H, Quintans-Júnior LJ, Martins N, Quintans JSS. Araújo-Filho HG, et al. Among authors: pereira ewm. Int Immunopharmacol. 2020 Sep;86:106766. doi: 10.1016/j.intimp.2020.106766. Epub 2020 Jul 8. Int Immunopharmacol. 2020. PMID: 32652504
Role of peripheral and central sensitization in the anti-hyperalgesic effect of hecogenin acetate, an acetylated sapogenin, complexed with β-cyclodextrin: Involvement of NFκB and p38 MAPK pathways.
Santos Passos FR, Pereira EWM, Heimfarth L, Monteiro BS, Barbosa Gomes de Carvalho YM, Siqueira-Lima PS, Melo Coutinho HD, Antunes de Souza Araújo A, Guedes da Silva Almeida JR, Barreto RSS, Picot L, Quintans-Júnior LJ, Quintans JSS. Santos Passos FR, et al. Among authors: pereira ewm. Neuropharmacology. 2021 Mar 15;186:108395. doi: 10.1016/j.neuropharm.2020.108395. Epub 2021 Jan 28. Neuropharmacology. 2021. PMID: 33516738
Pharmacological effects of a complex α-bisabolol/β-cyclodextrin in a mice arthritis model with involvement of IL-1β, IL-6 and MAPK.
Heimfarth L, Rezende MM, Pereira EWM, Passos FRS, Monteiro BS, Santos TKB, Lima NT, Souza ICL, de Albuquerque Junior RLC, de Souza Siqueira Lima P, de Souza Araújo AA, Quintans Júnior LJ, Kim B, Coutinho HDM, de Souza Siqueira Quintans J. Heimfarth L, et al. Among authors: pereira ewm. Biomed Pharmacother. 2022 Jul;151:113142. doi: 10.1016/j.biopha.2022.113142. Epub 2022 May 25. Biomed Pharmacother. 2022. PMID: 35623175 Free article.
16 results