Chng WJ - Search Results

1

EZH2 phosphorylation by JAK3 mediates a switch to noncanonical function in natural killer/T-cell lymphoma.

Yan J, Li B, Lin B, Lee PT, Chung TH, Tan J, Bi C, Lee XT, Selvarajan V, Ng SB, Yang H, Yu Q, Chng WJ. Yan J, et al. Among authors: chng wj. Blood. 2016 Aug 18;128(7):948-58. doi: 10.1182/blood-2016-01-690701. Epub 2016 Jun 13. Blood. 2016. PMID: 27297789 Free article.

2

Enhanced activation of STAT pathways and overexpression of survivin confer resistance to FLT3 inhibitors and could be therapeutic targets in AML.

Zhou J, Bi C, Janakakumara JV, Liu SC, Chng WJ, Tay KG, Poon LF, Xie Z, Palaniyandi S, Yu H, Glaser KB, Albert DH, Davidsen SK, Chen CS. Zhou J, et al. Among authors: chng wj. Blood. 2009 Apr 23;113(17):4052-62. doi: 10.1182/blood-2008-05-156422. Epub 2009 Jan 14. Blood. 2009. PMID: 19144991 Free article.

3

"Micro"-managing the MiRNome in SzS.

Chng WJ. Chng WJ. Blood. 2010 Aug 19;116(7):1021-2. doi: 10.1182/blood-2010-05-285189. Blood. 2010. PMID: 20724547 Free article. No abstract available.

4

Activated oncogenic pathways and therapeutic targets in extranodal nasal-type NK/T cell lymphoma revealed by gene expression profiling.

Ng SB, Selvarajan V, Huang G, Zhou J, Feldman AL, Law M, Kwong YL, Shimizu N, Kagami Y, Aozasa K, Salto-Tellez M, Chng WJ. Ng SB, et al. Among authors: chng wj. J Pathol. 2011 Mar;223(4):496-510. doi: 10.1002/path.2823. Epub 2011 Jan 5. J Pathol. 2011. PMID: 21294123

5

PRL-3, a metastasis associated tyrosine phosphatase, is involved in FLT3-ITD signaling and implicated in anti-AML therapy.

Zhou J, Bi C, Chng WJ, Cheong LL, Liu SC, Mahara S, Tay KG, Zeng Q, Li J, Guo K, Tan CP, Yu H, Albert DH, Chen CS. Zhou J, et al. Among authors: chng wj. PLoS One. 2011 May 12;6(5):e19798. doi: 10.1371/journal.pone.0019798. PLoS One. 2011. PMID: 21589872 Free PMC article.

6

Determinants of sensitivity to DZNep induced apoptosis in multiple myeloma cells.

Xie Z, Bi C, Cheong LL, Liu SC, Huang G, Zhou J, Yu Q, Chen CS, Chng WJ. Xie Z, et al. Among authors: chng wj. PLoS One. 2011;6(6):e21583. doi: 10.1371/journal.pone.0021583. Epub 2011 Jun 24. PLoS One. 2011. PMID: 21720561 Free PMC article.

7

The histone methyltransferase inhibitor, DZNep, up-regulates TXNIP, increases ROS production, and targets leukemia cells in AML.

Zhou J, Bi C, Cheong LL, Mahara S, Liu SC, Tay KG, Koh TL, Yu Q, Chng WJ. Zhou J, et al. Among authors: chng wj. Blood. 2011 Sep 8;118(10):2830-9. doi: 10.1182/blood-2010-07-294827. Epub 2011 Jul 6. Blood. 2011. PMID: 21734239 Free article.

8

Dysregulated microRNAs affect pathways and targets of biologic relevance in nasal-type natural killer/T-cell lymphoma.

Ng SB, Yan J, Huang G, Selvarajan V, Tay JL, Lin B, Bi C, Tan J, Kwong YL, Shimizu N, Aozasa K, Chng WJ. Ng SB, et al. Among authors: chng wj. Blood. 2011 Nov 3;118(18):4919-29. doi: 10.1182/blood-2011-07-364224. Epub 2011 Sep 14. Blood. 2011. PMID: 21921041 Free article.

9

TXNIP (VDUP-1, TBP-2): a major redox regulator commonly suppressed in cancer by epigenetic mechanisms.

Zhou J, Yu Q, Chng WJ. Zhou J, et al. Among authors: chng wj. Int J Biochem Cell Biol. 2011 Dec;43(12):1668-73. doi: 10.1016/j.biocel.2011.09.005. Epub 2011 Sep 24. Int J Biochem Cell Biol. 2011. PMID: 21964212 Review.

10

The pro-metastasis tyrosine phosphatase, PRL-3 (PTP4A3), is a novel mediator of oncogenic function of BCR-ABL in human chronic myeloid leukemia.

Zhou J, Cheong LL, Liu SC, Chong PS, Mahara S, Bi C, Ong KO, Zeng Q, Chng WJ. Zhou J, et al. Among authors: chng wj. Mol Cancer. 2012 Sep 21;11:72. doi: 10.1186/1476-4598-11-72. Mol Cancer. 2012. PMID: 22995644 Free PMC article.

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