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A conserved PLPLRT/SD motif of STING mediates the recruitment and activation of TBK1.
Zhao B, Du F, Xu P, Shu C, Sankaran B, Bell SL, Liu M, Lei Y, Gao X, Fu X, Zhu F, Liu Y, Laganowsky A, Zheng X, Ji JY, West AP, Watson RO, Li P. Zhao B, et al. Among authors: sankaran b. Nature. 2019 May;569(7758):718-722. doi: 10.1038/s41586-019-1228-x. Epub 2019 May 22. Nature. 2019. PMID: 31118511 Free PMC article.
The Structural Basis of IRF-3 Activation upon Phosphorylation.
Jing T, Zhao B, Xu P, Gao X, Chi L, Han H, Sankaran B, Li P. Jing T, et al. Among authors: sankaran b. J Immunol. 2020 Oct 1;205(7):1886-1896. doi: 10.4049/jimmunol.2000026. Epub 2020 Aug 21. J Immunol. 2020. PMID: 32826280 Free PMC article.
A Quick Route to Multiple Highly Potent SARS-CoV-2 Main Protease Inhibitors*.
Yang KS, Ma XR, Ma Y, Alugubelli YR, Scott DA, Vatansever EC, Drelich AK, Sankaran B, Geng ZZ, Blankenship LR, Ward HE, Sheng YJ, Hsu JC, Kratch KC, Zhao B, Hayatshahi HS, Liu J, Li P, Fierke CA, Tseng CK, Xu S, Liu WR. Yang KS, et al. Among authors: sankaran b. ChemMedChem. 2021 Mar 18;16(6):942-948. doi: 10.1002/cmdc.202000924. Epub 2020 Dec 10. ChemMedChem. 2021. PMID: 33283984 Free PMC article.
Structural basis for cyclic-nucleotide selectivity and cGMP-selective activation of PKG I.
Huang GY, Kim JJ, Reger AS, Lorenz R, Moon EW, Zhao C, Casteel DE, Bertinetti D, Vanschouwen B, Selvaratnam R, Pflugrath JW, Sankaran B, Melacini G, Herberg FW, Kim C. Huang GY, et al. Among authors: sankaran b. Structure. 2014 Jan 7;22(1):116-24. doi: 10.1016/j.str.2013.09.021. Epub 2013 Nov 14. Structure. 2014. PMID: 24239458 Free PMC article.
Structural plasticity of the coiled-coil domain of rotavirus NSP4.
Sastri NP, Viskovska M, Hyser JM, Tanner MR, Horton LB, Sankaran B, Prasad BV, Estes MK. Sastri NP, et al. Among authors: sankaran b. J Virol. 2014 Dec;88(23):13602-12. doi: 10.1128/JVI.02227-14. Epub 2014 Sep 17. J Virol. 2014. PMID: 25231315 Free PMC article.
Structure and mechanism of the ATPase that powers viral genome packaging.
Hilbert BJ, Hayes JA, Stone NP, Duffy CM, Sankaran B, Kelch BA. Hilbert BJ, et al. Among authors: sankaran b. Proc Natl Acad Sci U S A. 2015 Jul 21;112(29):E3792-9. doi: 10.1073/pnas.1506951112. Epub 2015 Jul 6. Proc Natl Acad Sci U S A. 2015. PMID: 26150523 Free PMC article.
240 results