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Poor-prognosis colon cancer is defined by a molecularly distinct subtype and develops from serrated precursor lesions.
De Sousa E Melo F, Wang X, Jansen M, Fessler E, Trinh A, de Rooij LP, de Jong JH, de Boer OJ, van Leersum R, Bijlsma MF, Rodermond H, van der Heijden M, van Noesel CJ, Tuynman JB, Dekker E, Markowetz F, Medema JP, Vermeulen L. De Sousa E Melo F, et al. Among authors: vermeulen l. Nat Med. 2013 May;19(5):614-8. doi: 10.1038/nm.3174. Epub 2013 Apr 14. Nat Med. 2013. PMID: 23584090
Balancing signals in the intestinal niche.
van Neerven SM, Vermeulen L. van Neerven SM, et al. Among authors: vermeulen l. EMBO J. 2017 Feb 15;36(4):389-391. doi: 10.15252/embj.201796431. Epub 2017 Feb 3. EMBO J. 2017. PMID: 28159860 Free PMC article.
Esophageal Adenocarcinoma Cells and Xenograft Tumors Exposed to Erb-b2 Receptor Tyrosine Kinase 2 and 3 Inhibitors Activate Transforming Growth Factor Beta Signaling, Which Induces Epithelial to Mesenchymal Transition.
Ebbing EA, Steins A, Fessler E, Stathi P, Lesterhuis WJ, Krishnadath KK, Vermeulen L, Medema JP, Bijlsma MF, van Laarhoven HWM. Ebbing EA, et al. Among authors: vermeulen l. Gastroenterology. 2017 Jul;153(1):63-76.e14. doi: 10.1053/j.gastro.2017.03.004. Epub 2017 Mar 9. Gastroenterology. 2017. PMID: 28286209
Molecular subtypes in cancers of the gastrointestinal tract.
Bijlsma MF, Sadanandam A, Tan P, Vermeulen L. Bijlsma MF, et al. Among authors: vermeulen l. Nat Rev Gastroenterol Hepatol. 2017 Jun;14(6):333-342. doi: 10.1038/nrgastro.2017.33. Epub 2017 Apr 12. Nat Rev Gastroenterol Hepatol. 2017. PMID: 28400627 Review.
Stem cell functionality is microenvironmentally defined during tumour expansion and therapy response in colon cancer.
Lenos KJ, Miedema DM, Lodestijn SC, Nijman LE, van den Bosch T, Romero Ros X, Lourenço FC, Lecca MC, van der Heijden M, van Neerven SM, van Oort A, Leveille N, Adam RS, de Sousa E Melo F, Otten J, Veerman P, Hypolite G, Koens L, Lyons SK, Stassi G, Winton DJ, Medema JP, Morrissey E, Bijlsma MF, Vermeulen L. Lenos KJ, et al. Among authors: vermeulen l. Nat Cell Biol. 2018 Oct;20(10):1193-1202. doi: 10.1038/s41556-018-0179-z. Epub 2018 Sep 3. Nat Cell Biol. 2018. PMID: 30177776 Free PMC article.
Cancer stem cells: here, there, and everywhere.
Lodestijn SC, Lenos KJ, Miedema DM, Bijlsma MF, Vermeulen L. Lodestijn SC, et al. Among authors: vermeulen l. Mol Cell Oncol. 2018 Dec 4;6(1):1540235. doi: 10.1080/23723556.2018.1540235. eCollection 2019. Mol Cell Oncol. 2018. PMID: 30788417 Free PMC article.
Spatiotemporal regulation of clonogenicity in colorectal cancer xenografts.
van der Heijden M, Miedema DM, Waclaw B, Veenstra VL, Lecca MC, Nijman LE, van Dijk E, van Neerven SM, Lodestijn SC, Lenos KJ, de Groot NE, Prasetyanti PR, Arricibita Varea A, Winton DJ, Medema JP, Morrissey E, Ylstra B, Nowak MA, Bijlsma MF, Vermeulen L. van der Heijden M, et al. Among authors: vermeulen l. Proc Natl Acad Sci U S A. 2019 Mar 26;116(13):6140-6145. doi: 10.1073/pnas.1813417116. Epub 2019 Mar 8. Proc Natl Acad Sci U S A. 2019. PMID: 30850544 Free PMC article.
CD31-positive microvessel density within adenomas of Lynch Syndrome patients is similar compared to adenomas of non-Lynch patients.
Vleugels JLA, van Neerven SM, van Leerdam ME, Wanders LK, de Wit M, Carvalho B, Delis-van Diemen PM, Kallenberg FGJ, Vermeulen L, Beliën JA, East JE, Meijer GA, Dekker E. Vleugels JLA, et al. Among authors: vermeulen l. Endosc Int Open. 2019 May;7(5):E701-E707. doi: 10.1055/a-0832-8283. Epub 2019 May 8. Endosc Int Open. 2019. PMID: 31073537 Free PMC article.
367 results