Hou J - Search Results

1

Discovery of BC-01, a novel mutual prodrug (hybrid drug) of ubenimex and fluorouracil as anticancer agent.

Jiang Y, Li X, Hou J, Huang Y, Jia Y, Zou M, Zhang J, Wang X, Xu W, Zhang Y. Jiang Y, et al. Among authors: hou j. Eur J Med Chem. 2016 Oct 4;121:649-657. doi: 10.1016/j.ejmech.2016.05.068. Epub 2016 Jun 1. Eur J Med Chem. 2016. PMID: 27322756

2

Discovery of the first N-hydroxycinnamamide-based histone deacetylase 1/3 dual inhibitors with potent oral antitumor activity.

Li X, Inks ES, Li X, Hou J, Chou CJ, Zhang J, Jiang Y, Zhang Y, Xu W. Li X, et al. Among authors: hou j. J Med Chem. 2014 Apr 24;57(8):3324-41. doi: 10.1021/jm401877m. Epub 2014 Apr 15. J Med Chem. 2014. PMID: 24694055 Free PMC article.

3

Development of 3-hydroxycinnamamide-based HDAC inhibitors with potent in vitro and in vivo anti-tumor activity.

Li X, Hou J, Li X, Jiang Y, Liu X, Mu W, Jin Y, Zhang Y, Xu W. Li X, et al. Among authors: hou j. Eur J Med Chem. 2015 Jan 7;89:628-37. doi: 10.1016/j.ejmech.2014.10.077. Epub 2014 Oct 29. Eur J Med Chem. 2015. PMID: 25462271

4

Enhanced anticancer activity of 5-FU in combination with Bestatin: Evidence in human tumor-derived cell lines and an H22 tumor-bearing mouse.

Li J, Wang X, Hou J, Huang Y, Zhang Y, Xu W. Li J, et al. Among authors: hou j. Drug Discov Ther. 2015 Feb;9(1):45-52. doi: 10.5582/ddt.2015.01006. Drug Discov Ther. 2015. PMID: 25788051 Free article.

5

Synthesis and biological evaluation of novel histone deacetylases inhibitors with nitric oxide releasing activity.

Duan W, Hou J, Chu X, Li X, Zhang J, Li J, Xu W, Zhang Y. Duan W, et al. Among authors: hou j. Bioorg Med Chem. 2015 Aug 1;23(15):4481-4488. doi: 10.1016/j.bmc.2015.06.015. Epub 2015 Jun 20. Bioorg Med Chem. 2015. PMID: 26122774

6

Design, synthesis, and antitumor evaluation of histone deacetylase inhibitors with L-phenylglycine scaffold.

Zhang Y, Li X, Hou J, Huang Y, Xu W. Zhang Y, et al. Among authors: hou j. Drug Des Devel Ther. 2015 Oct 8;9:5553-67. doi: 10.2147/DDDT.S94037. eCollection 2015. Drug Des Devel Ther. 2015. PMID: 26504374 Free PMC article.

7

Discovery of Multi-target Anticancer Agents Based on HDAC Inhibitor MS-275 and 5-FU.

Jiang Y, Li X, Li X, Hou J, Ding Y, Zhang J, Xu W, Zhang Y. Jiang Y, et al. Among authors: hou j. Med Chem. 2016;12(1):30-6. doi: 10.2174/1573406411666150714111045. Med Chem. 2016. PMID: 26711240

8

LJNK, an indoline-2,3-dione-based aminopeptidase N inhibitor with promising antitumor potency.

Hou J, Jin K, Li J, Jiang Y, Li X, Wang X, Huang Y, Zhang Y, Xu W. Hou J, et al. Anticancer Drugs. 2016 Jul;27(6):496-507. doi: 10.1097/CAD.0000000000000351. Anticancer Drugs. 2016. PMID: 26872309

9

Discovery of a novel chimeric ubenimex-gemcitabine with potent oral antitumor activity.

Jiang Y, Hou J, Li X, Huang Y, Wang X, Wu J, Zhang J, Xu W, Zhang Y. Jiang Y, et al. Among authors: hou j. Bioorg Med Chem. 2016 Nov 15;24(22):5787-5795. doi: 10.1016/j.bmc.2016.09.033. Epub 2016 Sep 14. Bioorg Med Chem. 2016. PMID: 27670098

10

Selective HDAC inhibitors with potent oral activity against leukemia and colorectal cancer: Design, structure-activity relationship and anti-tumor activity study.

Li X, Zhang Y, Jiang Y, Wu J, Inks ES, Chou CJ, Gao S, Hou J, Ding Q, Li J, Wang X, Huang Y, Xu W. Li X, et al. Among authors: hou j. Eur J Med Chem. 2017 Jul 7;134:185-206. doi: 10.1016/j.ejmech.2017.03.069. Epub 2017 Mar 30. Eur J Med Chem. 2017. PMID: 28415009 Free PMC article.

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