Sidhu SS - Search Results

1

PTP1B controls non-mitochondrial oxygen consumption by regulating RNF213 to promote tumour survival during hypoxia.

Banh RS, Iorio C, Marcotte R, Xu Y, Cojocari D, Rahman AA, Pawling J, Zhang W, Sinha A, Rose CM, Isasa M, Zhang S, Wu R, Virtanen C, Hitomi T, Habu T, Sidhu SS, Koizumi A, Wilkins SE, Kislinger T, Gygi SP, Schofield CJ, Dennis JW, Wouters BG, Neel BG. Banh RS, et al. Among authors: sidhu ss. Nat Cell Biol. 2016 Jul;18(7):803-813. doi: 10.1038/ncb3376. Epub 2016 Jun 20. Nat Cell Biol. 2016. PMID: 27323329 Free PMC article.

2

Development of inhibitors in the ubiquitination cascade.

Zhang W, Sidhu SS. Zhang W, et al. Among authors: sidhu ss. FEBS Lett. 2014 Jan 21;588(2):356-67. doi: 10.1016/j.febslet.2013.11.003. Epub 2013 Nov 12. FEBS Lett. 2014. PMID: 24239534 Free PMC article. Review.

3

Engineering cell signaling modulators from native protein-protein interactions.

Zhang W, Ben-David M, Sidhu SS. Zhang W, et al. Among authors: sidhu ss. Curr Opin Struct Biol. 2017 Aug;45:25-35. doi: 10.1016/j.sbi.2016.11.002. Epub 2016 Nov 17. Curr Opin Struct Biol. 2017. PMID: 27866084 Review.

4

Generation and Validation of Intracellular Ubiquitin Variant Inhibitors for USP7 and USP10.

Zhang W, Sartori MA, Makhnevych T, Federowicz KE, Dong X, Liu L, Nim S, Dong A, Yang J, Li Y, Haddad D, Ernst A, Heerding D, Tong Y, Moffat J, Sidhu SS. Zhang W, et al. Among authors: sidhu ss. J Mol Biol. 2017 Nov 10;429(22):3546-3560. doi: 10.1016/j.jmb.2017.05.025. Epub 2017 Jun 3. J Mol Biol. 2017. PMID: 28587923

5

A General Strategy for Discovery of Inhibitors and Activators of RING and U-box E3 Ligases with Ubiquitin Variants.

Gabrielsen M, Buetow L, Nakasone MA, Ahmed SF, Sibbet GJ, Smith BO, Zhang W, Sidhu SS, Huang DT. Gabrielsen M, et al. Among authors: sidhu ss. Mol Cell. 2017 Oct 19;68(2):456-470.e10. doi: 10.1016/j.molcel.2017.09.027. Mol Cell. 2017. PMID: 29053960 Free PMC article.

6

Drug development: Allosteric inhibitors hit USP7 hard.

Zhang W, Sidhu SS. Zhang W, et al. Among authors: sidhu ss. Nat Chem Biol. 2018 Jan 16;14(2):110-111. doi: 10.1038/nchembio.2557. Nat Chem Biol. 2018. PMID: 29337966 No abstract available.

7

Dynamics of PARKIN-Dependent Mitochondrial Ubiquitylation in Induced Neurons and Model Systems Revealed by Digital Snapshot Proteomics.

Ordureau A, Paulo JA, Zhang W, Ahfeldt T, Zhang J, Cohn EF, Hou Z, Heo JM, Rubin LL, Sidhu SS, Gygi SP, Harper JW. Ordureau A, et al. Among authors: sidhu ss. Mol Cell. 2018 Apr 19;70(2):211-227.e8. doi: 10.1016/j.molcel.2018.03.012. Epub 2018 Apr 12. Mol Cell. 2018. PMID: 29656925 Free PMC article.

8

Generating Intracellular Modulators of E3 Ligases and Deubiquitinases from Phage-Displayed Ubiquitin Variant Libraries.

Zhang W, Sidhu SS. Zhang W, et al. Among authors: sidhu ss. Methods Mol Biol. 2018;1844:101-119. doi: 10.1007/978-1-4939-8706-1_8. Methods Mol Biol. 2018. PMID: 30242706

9

Emerging drug development technologies targeting ubiquitination for cancer therapeutics.

Veggiani G, Gerpe MCR, Sidhu SS, Zhang W. Veggiani G, et al. Among authors: sidhu ss. Pharmacol Ther. 2019 Jul;199:139-154. doi: 10.1016/j.pharmthera.2019.03.003. Epub 2019 Mar 7. Pharmacol Ther. 2019. PMID: 30851297 Free PMC article. Review.

10

Identification and Characterization of Mutations in Ubiquitin Required for Non-covalent Dimer Formation.

Gabrielsen M, Buetow L, Kowalczyk D, Zhang W, Sidhu SS, Huang DT. Gabrielsen M, et al. Among authors: sidhu ss. Structure. 2019 Sep 3;27(9):1452-1459.e4. doi: 10.1016/j.str.2019.06.008. Epub 2019 Jul 11. Structure. 2019. PMID: 31303481 Free PMC article.

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