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Design and Development of a Series of Potent and Selective Type II Inhibitors of CDK8.
ACS Med Chem Lett. 2016 Apr 5;7(6):595-600. doi: 10.1021/acsmedchemlett.6b00044. eCollection 2016 Jun 9.
ACS Med Chem Lett. 2016.
PMID: 27326333
Free PMC article.
Development of a Potent, Specific CDK8 Kinase Inhibitor Which Phenocopies CDK8/19 Knockout Cells.
Koehler MF, Bergeron P, Blackwood EM, Bowman K, Clark KR, Firestein R, Kiefer JR, Maskos K, McCleland ML, Orren L, Salphati L, Schmidt S, Schneider EV, Wu J, Beresini MH.
Koehler MF, et al. Among authors: orren l.
ACS Med Chem Lett. 2016 Jan 6;7(3):223-8. doi: 10.1021/acsmedchemlett.5b00278. eCollection 2016 Mar 10.
ACS Med Chem Lett. 2016.
PMID: 26985305
Free PMC article.
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Small-Molecule Library Subset Screening as an Aid for Accelerating Lead Identification.
Beresini MH, Liu Y, Dawes TD, Clark KR, Orren L, Schmidt S, Turincio R, Jones SW, Rodriguez RA, Thana P, Hascall D, Gross DP, Skelton NJ.
Beresini MH, et al. Among authors: orren l.
J Biomol Screen. 2014 Jun;19(5):758-70. doi: 10.1177/1087057114522515. Epub 2014 Feb 11.
J Biomol Screen. 2014.
PMID: 24518067
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Compound Transfer by Acoustic Droplet Ejection Promotes Quality and Efficiency in Ultra-High-Throughput Screening Campaigns.
Dawes TD, Turincio R, Jones SW, Rodriguez RA, Gadiagellan D, Thana P, Clark KR, Gustafson AE, Orren L, Liimatta M, Gross DP, Maurer T, Beresini MH.
Dawes TD, et al. Among authors: orren l.
J Lab Autom. 2016 Feb;21(1):64-75. doi: 10.1177/2211068215590588. Epub 2015 Jun 15.
J Lab Autom. 2016.
PMID: 26077161
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