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A multicenter assessment of single-cell models aligned to standard measures of cell health for prediction of acute hepatotoxicity.
Sison-Young RL, Lauschke VM, Johann E, Alexandre E, Antherieu S, Aerts H, Gerets HHJ, Labbe G, Hoët D, Dorau M, Schofield CA, Lovatt CA, Holder JC, Stahl SH, Richert L, Kitteringham NR, Jones RP, Elmasry M, Weaver RJ, Hewitt PG, Ingelman-Sundberg M, Goldring CE, Park BK. Sison-Young RL, et al. Among authors: aerts h. Arch Toxicol. 2017 Mar;91(3):1385-1400. doi: 10.1007/s00204-016-1745-4. Epub 2016 Jun 25. Arch Toxicol. 2017. PMID: 27344343 Free PMC article.
Comparative Proteomic Characterization of 4 Human Liver-Derived Single Cell Culture Models Reveals Significant Variation in the Capacity for Drug Disposition, Bioactivation, and Detoxication.
Sison-Young RL, Mitsa D, Jenkins RE, Mottram D, Alexandre E, Richert L, Aerts H, Weaver RJ, Jones RP, Johann E, Hewitt PG, Ingelman-Sundberg M, Goldring CE, Kitteringham NR, Park BK. Sison-Young RL, et al. Among authors: aerts h. Toxicol Sci. 2015 Oct;147(2):412-24. doi: 10.1093/toxsci/kfv136. Epub 2015 Jul 8. Toxicol Sci. 2015. PMID: 26160117 Free PMC article.
Ultrasensitive ctDNA detection for preoperative disease stratification in early-stage lung adenocarcinoma.
Black JRM, Bartha G, Abbott CW, Boyle SM, Karasaki T, Li B, Chen R, Harris J, Veeriah S, Colopi M, Bakir MA, Liu WK, Lyle J, Navarro FCP, Northcott J, Pyke RM, Hill MS, Thol K, Huebner A, Bailey C, Colliver EC, Martínez-Ruiz C, Grigoriadis K, Pawlik P, Moore DA, Marinelli D, Shutkever OG, Murphy C, Sivakumar M; TRACERx consortium; Shaw JA, Hackshaw A, McGranahan N, Jamal-Hanjani M, Frankell AM, Chen RO, Swanton C. Black JRM, et al. Nat Med. 2025 Jan;31(1):70-76. doi: 10.1038/s41591-024-03216-y. Epub 2025 Jan 13. Nat Med. 2025. PMID: 39806071 Free PMC article.
Prospective validation of ORACLE, a clonal expression biomarker associated with survival of patients with lung adenocarcinoma.
Biswas D, Liu YH, Herrero J, Wu Y, Moore DA, Karasaki T, Grigoriadis K, Lu WT, Veeriah S, Naceur-Lombardelli C, Magno N, Ward S, Frankell AM, Hill MS, Colliver E, de Carné Trécesson S, East P, Malhi A, Snell DM, O'Neill O, Leonce D, Mattsson J, Lindberg A, Micke P, Moldvay J, Megyesfalvi Z, Dome B, Fillinger J, Nicod J, Downward J, Szallasi Z; TRACERx Consortium; Hackshaw A, Jamal-Hanjani M, Kanu N, Birkbak NJ, Swanton C. Biswas D, et al. Nat Cancer. 2025 Jan 9. doi: 10.1038/s43018-024-00883-1. Online ahead of print. Nat Cancer. 2025. PMID: 39789179
Anatomy-centred deep learning improves generalisability and progression prediction in radiographic sacroiliitis detection.
Dorfner FJ, Vahldiek JL, Donle L, Zhukov A, Xu L, Häntze H, Makowski MR, Aerts HJWL, Proft F, Rios Rodriguez V, Rademacher J, Protopopov M, Haibel H, Hermann KG, Diekhoff T, Adams LC, Torgutalp M, Poddubnyy D, Bressem KK. Dorfner FJ, et al. Among authors: aerts hjwl. RMD Open. 2024 Dec 23;10(4):e004628. doi: 10.1136/rmdopen-2024-004628. RMD Open. 2024. PMID: 39719299 Free PMC article.
A foundation model for generalized brain MRI analysis.
Tak D, Garomsa BA, Chaunzwa TL, Zapaishchykova A, Climent Pardo JC, Ye Z, Zielke J, Ravipati Y, Vajapeyam S, Mahootiha M, Smith C, Familiar AM, Liu KX, Prabhu S, Bandopadhayay P, Nabavizadeh A, Mueller S, Aerts HJ, Huang RY, Poussaint TY, Kann BH. Tak D, et al. Among authors: aerts hj. medRxiv [Preprint]. 2024 Dec 3:2024.12.02.24317992. doi: 10.1101/2024.12.02.24317992. medRxiv. 2024. PMID: 39677480 Free PMC article. Preprint.
286 results