Egli M - Search Results

1

Structural Insights into Conformation Differences between DNA/TNA and RNA/TNA Chimeric Duplexes.

Anosova I, Kowal EA, Sisco NJ, Sau S, Liao JY, Bala S, Rozners E, Egli M, Chaput JC, Van Horn WD. Anosova I, et al. Among authors: egli m. Chembiochem. 2016 Sep 15;17(18):1705-8. doi: 10.1002/cbic.201600349. Epub 2016 Jul 29. Chembiochem. 2016. PMID: 27347671 Free PMC article.

2

Crystal structure of a B-form DNA duplex containing (L)-alpha-threofuranosyl (3'-->2') nucleosides: a four-carbon sugar is easily accommodated into the backbone of DNA.

Wilds CJ, Wawrzak Z, Krishnamurthy R, Eschenmoser A, Egli M. Wilds CJ, et al. Among authors: egli m. J Am Chem Soc. 2002 Nov 20;124(46):13716-21. doi: 10.1021/ja0207807. J Am Chem Soc. 2002. PMID: 12431101

3

Why does TNA cross-pair more strongly with RNA than with DNA? an answer from X-ray analysis.

Pallan PS, Wilds CJ, Wawrzak Z, Krishnamurthy R, Eschenmoser A, Egli M. Pallan PS, et al. Among authors: egli m. Angew Chem Int Ed Engl. 2003;42(47):5893-5. doi: 10.1002/anie.200352553. Angew Chem Int Ed Engl. 2003. PMID: 14673929 No abstract available.

4

"Deoxyribo nanonucleic acid"; antiparallel, parallel, and unparalleled.

Egli M. Egli M. Chem Biol. 2004 Aug;11(8):1027-9. doi: 10.1016/j.chembiol.2004.08.002. Chem Biol. 2004. PMID: 15324800

5

Structural rationalization of a large difference in RNA affinity despite a small difference in chemistry between two 2'-O-modified nucleic acid analogues.

Pattanayek R, Sethaphong L, Pan C, Prhavc M, Prakash TP, Manoharan M, Egli M. Pattanayek R, et al. Among authors: egli m. J Am Chem Soc. 2004 Nov 24;126(46):15006-7. doi: 10.1021/ja044637k. J Am Chem Soc. 2004. PMID: 15547979

6

The long and winding road to the structure of homo-DNA.

Egli M, Lubini P, Pallan PS. Egli M, et al. Chem Soc Rev. 2007 Jan;36(1):31-45. doi: 10.1039/b606807c. Epub 2006 Oct 3. Chem Soc Rev. 2007. PMID: 17173143 Review.

7

Crystal structure, stability and in vitro RNAi activity of oligoribonucleotides containing the ribo-difluorotoluyl nucleotide: insights into substrate requirements by the human RISC Ago2 enzyme.

Li F, Pallan PS, Maier MA, Rajeev KG, Mathieu SL, Kreutz C, Fan Y, Sanghvi J, Micura R, Rozners E, Manoharan M, Egli M. Li F, et al. Among authors: egli m. Nucleic Acids Res. 2007;35(19):6424-38. doi: 10.1093/nar/gkm664. Epub 2007 Sep 18. Nucleic Acids Res. 2007. PMID: 17881374 Free PMC article.

8

Backbone-base inclination as a fundamental determinant of nucleic acid self- and cross-pairing.

Pallan PS, Lubini P, Bolli M, Egli M. Pallan PS, et al. Among authors: egli m. Nucleic Acids Res. 2007;35(19):6611-24. doi: 10.1093/nar/gkm612. Epub 2007 Sep 28. Nucleic Acids Res. 2007. PMID: 17905816 Free PMC article.

The crystal structure of the duplex formed by oligo(2',3'-dideoxy-beta-d-glucopyranosyl)nucleotides (homo-DNA) revealed strongly inclined backbone and base-pair axes [Egli,M., Pallan,P.S., Pattanayek,R., Wilds,C.J., Lubini,P., Minasov,G., Dobler,M., Leumann,C …

The crystal structure of the duplex formed by oligo(2',3'-dideoxy-beta-d-glucopyranosyl)nucleotides (homo-DNA) revealed strongly inclined ba …

9

Pairing geometry of the hydrophobic thymine analogue 2,4-difluorotoluene in duplex DNA as analyzed by X-ray crystallography.

Pallan PS, Egli M. Pallan PS, et al. Among authors: egli m. J Am Chem Soc. 2009 Sep 9;131(35):12548-9. doi: 10.1021/ja905739j. J Am Chem Soc. 2009. PMID: 19685868 Free PMC article.

10

Interplay of structure, hydration and thermal stability in formacetal modified oligonucleotides: RNA may tolerate nonionic modifications better than DNA.

Kolarovic A, Schweizer E, Greene E, Gironda M, Pallan PS, Egli M, Rozners E. Kolarovic A, et al. Among authors: egli m. J Am Chem Soc. 2009 Oct 21;131(41):14932-7. doi: 10.1021/ja904926e. J Am Chem Soc. 2009. PMID: 19824732 Free PMC article.

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