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Page 1
Proteasome machinery is instrumental in a common gain-of-function program of the p53 missense mutants in cancer.
Walerych D, Lisek K, Sommaggio R, Piazza S, Ciani Y, Dalla E, Rajkowska K, Gaweda-Walerych K, Ingallina E, Tonelli C, Morelli MJ, Amato A, Eterno V, Zambelli A, Rosato A, Amati B, Wiśniewski JR, Del Sal G. Walerych D, et al. Among authors: ingallina e. Nat Cell Biol. 2016 Aug;18(8):897-909. doi: 10.1038/ncb3380. Epub 2016 Jun 27. Nat Cell Biol. 2016. PMID: 27347849 Free article.
Metabolic control of YAP and TAZ by the mevalonate pathway.
Sorrentino G, Ruggeri N, Specchia V, Cordenonsi M, Mano M, Dupont S, Manfrin A, Ingallina E, Sommaggio R, Piazza S, Rosato A, Piccolo S, Del Sal G. Sorrentino G, et al. Among authors: ingallina e. Nat Cell Biol. 2014 Apr;16(4):357-66. doi: 10.1038/ncb2936. Epub 2014 Mar 23. Nat Cell Biol. 2014. PMID: 24658687
Mechanical cues control mutant p53 stability through a mevalonate-RhoA axis.
Ingallina E, Sorrentino G, Bertolio R, Lisek K, Zannini A, Azzolin L, Severino LU, Scaini D, Mano M, Mantovani F, Rosato A, Bicciato S, Piccolo S, Del Sal G. Ingallina E, et al. Nat Cell Biol. 2018 Jan;20(1):28-35. doi: 10.1038/s41556-017-0009-8. Epub 2017 Dec 18. Nat Cell Biol. 2018. PMID: 29255172 Free PMC article.
YAP enhances the pro-proliferative transcriptional activity of mutant p53 proteins.
Di Agostino S, Sorrentino G, Ingallina E, Valenti F, Ferraiuolo M, Bicciato S, Piazza S, Strano S, Del Sal G, Blandino G. Di Agostino S, et al. Among authors: ingallina e. EMBO Rep. 2016 Feb;17(2):188-201. doi: 10.15252/embr.201540488. Epub 2015 Dec 21. EMBO Rep. 2016. PMID: 26691213 Free PMC article.
Glucocorticoid receptor signalling activates YAP in breast cancer.
Sorrentino G, Ruggeri N, Zannini A, Ingallina E, Bertolio R, Marotta C, Neri C, Cappuzzello E, Forcato M, Rosato A, Mano M, Bicciato S, Del Sal G. Sorrentino G, et al. Among authors: ingallina e. Nat Commun. 2017 Jan 19;8:14073. doi: 10.1038/ncomms14073. Nat Commun. 2017. PMID: 28102225 Free PMC article.