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Patient-derived xenotransplants can recapitulate the genetic driver landscape of acute leukemias.
Wang K, Sanchez-Martin M, Wang X, Knapp KM, Koche R, Vu L, Nahas MK, He J, Hadler M, Stein EM, Tallman MS, Donahue AL, Frampton GM, Lipson D, Roels S, Stephens PJ, Sanford EM, Brennan T, Otto GA, Yelensky R, Miller VA, Kharas MG, Levine RL, Ferrando A, Armstrong SA, Krivtsov AV. Wang K, et al. Among authors: he j. Leukemia. 2017 Jan;31(1):151-158. doi: 10.1038/leu.2016.166. Epub 2016 Jun 13. Leukemia. 2017. PMID: 27363283 Free PMC article.
Novel PDGFRB fusions in childhood B- and T-acute lymphoblastic leukemia.
Heilmann AM, Schrock AB, He J, Nahas M, Curran K, Shukla N, Cramer S, Draper L, Verma A, Erlich R, Ross J, Stephens P, Miller VA, Ali SM, Verglio JA, Tallman MS, Mughal TI. Heilmann AM, et al. Among authors: he j. Leukemia. 2017 Sep;31(9):1989-1992. doi: 10.1038/leu.2017.161. Epub 2017 May 29. Leukemia. 2017. PMID: 28552906 No abstract available.
Bi-allelic inactivation is more prevalent at relapse in multiple myeloma, identifying RB1 as an independent prognostic marker.
Chavan SS, He J, Tytarenko R, Deshpande S, Patel P, Bailey M, Stein CK, Stephens O, Weinhold N, Petty N, Steward D, Rasche L, Bauer M, Ashby C, Peterson E, Ali S, Ross J, Miller VA, Stephens P, Thanendrarajan S, Schinke C, Zangari M, van Rhee F, Barlogie B, Mughal TI, Davies FE, Morgan GJ, Walker BA. Chavan SS, et al. Among authors: he j. Blood Cancer J. 2017 Feb 24;7(2):e535. doi: 10.1038/bcj.2017.12. Blood Cancer J. 2017. PMID: 28234347 Free PMC article.
Small molecule inhibits KCNQ channels with a non-blocking mechanism.
Li J, Yang Z, Zhang S, Ye Y, He J, Zhang Y, Han H, Kong W, Liu J, Min Y, Shen J, Mei L, Chen Z, Hou P, Guo J, Zhang Q, Yang H. Li J, et al. Among authors: he j. Nat Chem Biol. 2025 Jan 15. doi: 10.1038/s41589-024-01834-8. Online ahead of print. Nat Chem Biol. 2025. PMID: 39814994
35,078 results
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