Aittokallio T - Search Results

1

Systematic drug screening reveals specific vulnerabilities and co-resistance patterns in endocrine-resistant breast cancer.

Kangaspeska S, Hultsch S, Jaiswal A, Edgren H, Mpindi JP, Eldfors S, Brück O, Aittokallio T, Kallioniemi O. Kangaspeska S, et al. Among authors: aittokallio t. BMC Cancer. 2016 Jul 4;16:378. doi: 10.1186/s12885-016-2452-5. BMC Cancer. 2016. PMID: 27378269 Free PMC article.

2

Individualized systems medicine strategy to tailor treatments for patients with chemorefractory acute myeloid leukemia.

Pemovska T, Kontro M, Yadav B, Edgren H, Eldfors S, Szwajda A, Almusa H, Bespalov MM, Ellonen P, Elonen E, Gjertsen BT, Karjalainen R, Kulesskiy E, Lagström S, Lehto A, Lepistö M, Lundán T, Majumder MM, Marti JM, Mattila P, Murumägi A, Mustjoki S, Palva A, Parsons A, Pirttinen T, Rämet ME, Suvela M, Turunen L, Västrik I, Wolf M, Knowles J, Aittokallio T, Heckman CA, Porkka K, Kallioniemi O, Wennerberg K. Pemovska T, et al. Among authors: aittokallio t. Cancer Discov. 2013 Dec;3(12):1416-29. doi: 10.1158/2159-8290.CD-13-0350. Epub 2013 Sep 20. Cancer Discov. 2013. PMID: 24056683

3

A community effort to assess and improve drug sensitivity prediction algorithms.

Costello JC, Heiser LM, Georgii E, Gönen M, Menden MP, Wang NJ, Bansal M, Ammad-ud-din M, Hintsanen P, Khan SA, Mpindi JP, Kallioniemi O, Honkela A, Aittokallio T, Wennerberg K; NCI DREAM Community; Collins JJ, Gallahan D, Singer D, Saez-Rodriguez J, Kaski S, Gray JW, Stolovitzky G. Costello JC, et al. Among authors: aittokallio t. Nat Biotechnol. 2014 Dec;32(12):1202-12. doi: 10.1038/nbt.2877. Epub 2014 Jun 1. Nat Biotechnol. 2014. PMID: 24880487 Free PMC article.

4

Quantitative scoring of differential drug sensitivity for individually optimized anticancer therapies.

Yadav B, Pemovska T, Szwajda A, Kulesskiy E, Kontro M, Karjalainen R, Majumder MM, Malani D, Murumägi A, Knowles J, Porkka K, Heckman C, Kallioniemi O, Wennerberg K, Aittokallio T. Yadav B, et al. Among authors: aittokallio t. Sci Rep. 2014 Jun 5;4:5193. doi: 10.1038/srep05193. Sci Rep. 2014. PMID: 24898935 Free PMC article.

5

MicroRNA-135b regulates ERα, AR and HIF1AN and affects breast and prostate cancer cell growth.

Aakula A, Leivonen SK, Hintsanen P, Aittokallio T, Ceder Y, Børresen-Dale AL, Perälä M, Östling P, Kallioniemi O. Aakula A, et al. Among authors: aittokallio t. Mol Oncol. 2015 Aug;9(7):1287-300. doi: 10.1016/j.molonc.2015.03.001. Epub 2015 Mar 21. Mol Oncol. 2015. PMID: 25907805 Free PMC article.

6

Systematic Mapping of Kinase Addiction Combinations in Breast Cancer Cells by Integrating Drug Sensitivity and Selectivity Profiles.

Szwajda A, Gautam P, Karhinen L, Jha SK, Saarela J, Shakyawar S, Turunen L, Yadav B, Tang J, Wennerberg K, Aittokallio T. Szwajda A, et al. Among authors: aittokallio t. Chem Biol. 2015 Aug 20;22(8):1144-55. doi: 10.1016/j.chembiol.2015.06.021. Epub 2015 Jul 23. Chem Biol. 2015. PMID: 26211361

7

Impact of normalization methods on high-throughput screening data with high hit rates and drug testing with dose-response data.

Mpindi JP, Swapnil P, Dmitrii B, Jani S, Saeed K, Wennerberg K, Aittokallio T, Östling P, Kallioniemi O. Mpindi JP, et al. Among authors: aittokallio t. Bioinformatics. 2015 Dec 1;31(23):3815-21. doi: 10.1093/bioinformatics/btv455. Epub 2015 Aug 7. Bioinformatics. 2015. PMID: 26254433 Free PMC article.

8

Specific cancer-associated mutations in the switch III region of Ras increase tumorigenicity by nanocluster augmentation.

Šolman M, Ligabue A, Blaževitš O, Jaiswal A, Zhou Y, Liang H, Lectez B, Kopra K, Guzmán C, Härmä H, Hancock JF, Aittokallio T, Abankwa D. Šolman M, et al. Among authors: aittokallio t. Elife. 2015 Aug 14;4:e08905. doi: 10.7554/eLife.08905. Elife. 2015. PMID: 26274561 Free PMC article.

9

Systematic Identification of MicroRNAs That Impact on Proliferation of Prostate Cancer Cells and Display Changed Expression in Tumor Tissue.

Aakula A, Kohonen P, Leivonen SK, Mäkelä R, Hintsanen P, Mpindi JP, Martens-Uzunova E, Aittokallio T, Jenster G, Perälä M, Kallioniemi O, Östling P. Aakula A, et al. Among authors: aittokallio t. Eur Urol. 2016 Jun;69(6):1120-8. doi: 10.1016/j.eururo.2015.09.019. Epub 2015 Oct 20. Eur Urol. 2016. PMID: 26489476

10

Relevance Rank Platform (RRP) for Functional Filtering of High Content Protein-Protein Interaction Data.

Pokharel YR, Saarela J, Szwajda A, Rupp C, Rokka A, Lal Kumar Karna S, Teittinen K, Corthals G, Kallioniemi O, Wennerberg K, Aittokallio T, Westermarck J. Pokharel YR, et al. Among authors: aittokallio t. Mol Cell Proteomics. 2015 Dec;14(12):3274-83. doi: 10.1074/mcp.M115.050773. Epub 2015 Oct 23. Mol Cell Proteomics. 2015. PMID: 26499835 Free PMC article.

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