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SQSTM1/p62 mediates crosstalk between autophagy and the UPS in DNA repair.
Hewitt G, Carroll B, Sarallah R, Correia-Melo C, Ogrodnik M, Nelson G, Otten EG, Manni D, Antrobus R, Morgan BA, von Zglinicki T, Jurk D, Seluanov A, Gorbunova V, Johansen T, Passos JF, Korolchuk VI. Hewitt G, et al. Among authors: manni d. Autophagy. 2016 Oct 2;12(10):1917-1930. doi: 10.1080/15548627.2016.1210368. Epub 2016 Jul 8. Autophagy. 2016. PMID: 27391408 Free PMC article.
Oxidation of SQSTM1/p62 mediates the link between redox state and protein homeostasis.
Carroll B, Otten EG, Manni D, Stefanatos R, Menzies FM, Smith GR, Jurk D, Kenneth N, Wilkinson S, Passos JF, Attems J, Veal EA, Teyssou E, Seilhean D, Millecamps S, Eskelinen EL, Bronowska AK, Rubinsztein DC, Sanz A, Korolchuk VI. Carroll B, et al. Among authors: manni d. Nat Commun. 2018 Jan 17;9(1):256. doi: 10.1038/s41467-017-02746-z. Nat Commun. 2018. PMID: 29343728 Free PMC article.
Oxidative Stress by Monoamine Oxidase-A Impairs Transcription Factor EB Activation and Autophagosome Clearance, Leading to Cardiomyocyte Necrosis and Heart Failure.
Santin Y, Sicard P, Vigneron F, Guilbeau-Frugier C, Dutaur M, Lairez O, Couderc B, Manni D, Korolchuk VI, Lezoualc'h F, Parini A, Mialet-Perez J. Santin Y, et al. Among authors: manni d. Antioxid Redox Signal. 2016 Jul 1;25(1):10-27. doi: 10.1089/ars.2015.6522. Epub 2016 Apr 22. Antioxid Redox Signal. 2016. PMID: 26959532