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Human NK cells maintain licensing status and are subject to killer immunoglobulin-like receptor (KIR) and KIR-ligand inhibition following ex vivo expansion.
Wang W, Erbe AK, Alderson KA, Phillips E, Gallenberger M, Gan J, Campana D, Hank JA, Sondel PM. Wang W, et al. Among authors: alderson ka. Cancer Immunol Immunother. 2016 Sep;65(9):1047-59. doi: 10.1007/s00262-016-1864-z. Epub 2016 Jul 8. Cancer Immunol Immunother. 2016. PMID: 27392940 Free PMC article.
Out-of-Sequence Signal 3 Paralyzes Primary CD4(+) T-Cell-Dependent Immunity.
Sckisel GD, Bouchlaka MN, Monjazeb AM, Crittenden M, Curti BD, Wilkins DE, Alderson KA, Sungur CM, Ames E, Mirsoian A, Reddy A, Alexander W, Soulika A, Blazar BR, Longo DL, Wiltrout RH, Murphy WJ. Sckisel GD, et al. Among authors: alderson ka. Immunity. 2015 Aug 18;43(2):240-50. doi: 10.1016/j.immuni.2015.06.023. Epub 2015 Jul 28. Immunity. 2015. PMID: 26231116 Free PMC article.