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143 results

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Page 1
Identification of proliferative and mature β-cells in the islets of Langerhans.
Bader E, Migliorini A, Gegg M, Moruzzi N, Gerdes J, Roscioni SS, Bakhti M, Brandl E, Irmler M, Beckers J, Aichler M, Feuchtinger A, Leitzinger C, Zischka H, Wang-Sattler R, Jastroch M, Tschöp M, Machicao F, Staiger H, Häring HU, Chmelova H, Chouinard JA, Oskolkov N, Korsgren O, Speier S, Lickert H. Bader E, et al. Among authors: irmler m. Nature. 2016 Jul 21;535(7612):430-4. doi: 10.1038/nature18624. Epub 2016 Jul 11. Nature. 2016. PMID: 27398620
Insights into energy balance dysregulation from a mouse model of methylmalonic aciduria.
Lucienne M, Gerlini R, Rathkolb B, Calzada-Wack J, Forny P, Wueest S, Kaech A, Traversi F, Forny M, Bürer C, Aguilar-Pimentel A, Irmler M, Beckers J, Sauer S, Kölker S, Dewulf JP, Bommer GT, Hoces D, Gailus-Durner V, Fuchs H, Rozman J, Froese DS, Baumgartner MR, de Angelis MH. Lucienne M, et al. Among authors: irmler m. Hum Mol Genet. 2023 Aug 26;32(17):2717-2734. doi: 10.1093/hmg/ddad100. Hum Mol Genet. 2023. PMID: 37369025 Free PMC article.
Targeted estrogen delivery reverses the metabolic syndrome.
Finan B, Yang B, Ottaway N, Stemmer K, Müller TD, Yi CX, Habegger K, Schriever SC, García-Cáceres C, Kabra DG, Hembree J, Holland J, Raver C, Seeley RJ, Hans W, Irmler M, Beckers J, de Angelis MH, Tiano JP, Mauvais-Jarvis F, Perez-Tilve D, Pfluger P, Zhang L, Gelfanov V, DiMarchi RD, Tschöp MH. Finan B, et al. Among authors: irmler m. Nat Med. 2012 Dec;18(12):1847-56. doi: 10.1038/nm.3009. Epub 2012 Nov 11. Nat Med. 2012. PMID: 23142820 Free PMC article.
Cytokine response of primary human myotubes in an in vitro exercise model.
Scheler M, Irmler M, Lehr S, Hartwig S, Staiger H, Al-Hasani H, Beckers J, de Angelis MH, Häring HU, Weigert C. Scheler M, et al. Among authors: irmler m. Am J Physiol Cell Physiol. 2013 Oct 15;305(8):C877-86. doi: 10.1152/ajpcell.00043.2013. Epub 2013 Aug 7. Am J Physiol Cell Physiol. 2013. PMID: 23926130 Free article.
ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition.
Doll S, Proneth B, Tyurina YY, Panzilius E, Kobayashi S, Ingold I, Irmler M, Beckers J, Aichler M, Walch A, Prokisch H, Trümbach D, Mao G, Qu F, Bayir H, Füllekrug J, Scheel CH, Wurst W, Schick JA, Kagan VE, Angeli JP, Conrad M. Doll S, et al. Among authors: irmler m. Nat Chem Biol. 2017 Jan;13(1):91-98. doi: 10.1038/nchembio.2239. Epub 2016 Nov 14. Nat Chem Biol. 2017. PMID: 27842070 Free PMC article.
Genome-wide analysis of PDX1 target genes in human pancreatic progenitors.
Wang X, Sterr M, Burtscher I, Chen S, Hieronimus A, Machicao F, Staiger H, Häring HU, Lederer G, Meitinger T, Cernilogar FM, Schotta G, Irmler M, Beckers J, Hrabě de Angelis M, Ray M, Wright CVE, Bakhti M, Lickert H. Wang X, et al. Among authors: irmler m. Mol Metab. 2018 Mar;9:57-68. doi: 10.1016/j.molmet.2018.01.011. Epub 2018 Jan 31. Mol Metab. 2018. PMID: 29396371 Free PMC article.
Point mutations in the PDX1 transactivation domain impair human β-cell development and function.
Wang X, Sterr M, Ansarullah, Burtscher I, Böttcher A, Beckenbauer J, Siehler J, Meitinger T, Häring HU, Staiger H, Cernilogar FM, Schotta G, Irmler M, Beckers J, Wright CVE, Bakhti M, Lickert H. Wang X, et al. Among authors: irmler m. Mol Metab. 2019 Jun;24:80-97. doi: 10.1016/j.molmet.2019.03.006. Epub 2019 Mar 20. Mol Metab. 2019. PMID: 30930126 Free PMC article.
Generation of pancreatic β cells from CD177+ anterior definitive endoderm.
Mahaddalkar PU, Scheibner K, Pfluger S, Ansarullah, Sterr M, Beckenbauer J, Irmler M, Beckers J, Knöbel S, Lickert H. Mahaddalkar PU, et al. Among authors: irmler m. Nat Biotechnol. 2020 Sep;38(9):1061-1072. doi: 10.1038/s41587-020-0492-5. Epub 2020 Apr 27. Nat Biotechnol. 2020. PMID: 32341565
143 results