Bompiani KM - Search Results

1

Conformationally selective RNA aptamers allosterically modulate the β2-adrenoceptor.

Kahsai AW, Wisler JW, Lee J, Ahn S, Cahill Iii TJ, Dennison SM, Staus DP, Thomsen AR, Anasti KM, Pani B, Wingler LM, Desai H, Bompiani KM, Strachan RT, Qin X, Alam SM, Sullenger BA, Lefkowitz RJ. Kahsai AW, et al. Among authors: bompiani km. Nat Chem Biol. 2016 Sep;12(9):709-16. doi: 10.1038/nchembio.2126. Epub 2016 Jul 11. Nat Chem Biol. 2016. PMID: 27398998 Free PMC article.

2

Antidote control of aptamer therapeutics: the road to a safer class of drug agents.

Bompiani KM, Woodruff RS, Becker RC, Nimjee SM, Sullenger BA. Bompiani KM, et al. Curr Pharm Biotechnol. 2012 Aug;13(10):1924-34. doi: 10.2174/138920112802273137. Curr Pharm Biotechnol. 2012. PMID: 22352726 Review.

3

Synergistic effect of aptamers that inhibit exosites 1 and 2 on thrombin.

Nimjee SM, Oney S, Volovyk Z, Bompiani KM, Long SB, Hoffman M, Sullenger BA. Nimjee SM, et al. Among authors: bompiani km. RNA. 2009 Dec;15(12):2105-11. doi: 10.1261/rna.1240109. Epub 2009 Oct 21. RNA. 2009. PMID: 19846574 Free PMC article.

4

Probing the coagulation pathway with aptamers identifies combinations that synergistically inhibit blood clot formation.

Bompiani KM, Lohrmann JL, Pitoc GA, Frederiksen JW, Mackensen GB, Sullenger BA. Bompiani KM, et al. Chem Biol. 2014 Aug 14;21(8):935-44. doi: 10.1016/j.chembiol.2014.05.016. Epub 2014 Jul 24. Chem Biol. 2014. PMID: 25065530 Free PMC article.

5

Targeting Two Coagulation Cascade Proteases with a Bivalent Aptamer Yields a Potent and Antidote-Controllable Anticoagulant.

Soule EE, Bompiani KM, Woodruff RS, Sullenger BA. Soule EE, et al. Among authors: bompiani km. Nucleic Acid Ther. 2016 Feb;26(1):1-9. doi: 10.1089/nat.2015.0565. Epub 2015 Nov 19. Nucleic Acid Ther. 2016. PMID: 26584417 Free PMC article.

6

A high affinity, antidote-controllable prothrombin and thrombin-binding RNA aptamer inhibits thrombin generation and thrombin activity.

Bompiani KM, Monroe DM, Church FC, Sullenger BA. Bompiani KM, et al. J Thromb Haemost. 2012 May;10(5):870-80. doi: 10.1111/j.1538-7836.2012.04679.x. J Thromb Haemost. 2012. PMID: 22385910 Free PMC article.

7

Development of universal antidotes to control aptamer activity.

Oney S, Lam RT, Bompiani KM, Blake CM, Quick G, Heidel JD, Liu JY, Mack BC, Davis ME, Leong KW, Sullenger BA. Oney S, et al. Among authors: bompiani km. Nat Med. 2009 Oct;15(10):1224-8. doi: 10.1038/nm.1990. Epub 2009 Oct 4. Nat Med. 2009. PMID: 19801990 Free PMC article.

8

Combination of aptamer and drug for reversible anticoagulation in cardiopulmonary bypass.

Gunaratne R, Kumar S, Frederiksen JW, Stayrook S, Lohrmann JL, Perry K, Bompiani KM, Chabata CV, Thalji NK, Ho MD, Arepally G, Camire RM, Krishnaswamy S, Sullenger BA. Gunaratne R, et al. Among authors: bompiani km. Nat Biotechnol. 2018 Aug;36(7):606-613. doi: 10.1038/nbt.4153. Epub 2018 Jun 4. Nat Biotechnol. 2018. PMID: 29863725 Free PMC article.

9

Increased anticoagulant activity of thrombin-binding DNA aptamers by nanoscale organization on DNA nanostructures.

Rangnekar A, Zhang AM, Li SS, Bompiani KM, Hansen MN, Gothelf KV, Sullenger BA, LaBean TH. Rangnekar A, et al. Among authors: bompiani km. Nanomedicine. 2012 Jul;8(5):673-81. doi: 10.1016/j.nano.2011.08.011. Epub 2011 Sep 1. Nanomedicine. 2012. PMID: 21889476

10

Weave tile architecture construction strategy for DNA nanotechnology.

Hansen MN, Zhang AM, Rangnekar A, Bompiani KM, Carter JD, Gothelf KV, LaBean TH. Hansen MN, et al. Among authors: bompiani km. J Am Chem Soc. 2010 Oct 20;132(41):14481-6. doi: 10.1021/ja104456p. J Am Chem Soc. 2010. PMID: 20863133

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