Lefkowitz RJ - Search Results

1

Conformationally selective RNA aptamers allosterically modulate the β2-adrenoceptor.

Kahsai AW, Wisler JW, Lee J, Ahn S, Cahill Iii TJ, Dennison SM, Staus DP, Thomsen AR, Anasti KM, Pani B, Wingler LM, Desai H, Bompiani KM, Strachan RT, Qin X, Alam SM, Sullenger BA, Lefkowitz RJ. Kahsai AW, et al. Among authors: lefkowitz rj. Nat Chem Biol. 2016 Sep;12(9):709-16. doi: 10.1038/nchembio.2126. Epub 2016 Jul 11. Nat Chem Biol. 2016. PMID: 27398998 Free PMC article.

2

Isoprenylation in regulation of signal transduction by G-protein-coupled receptor kinases.

Inglese J, Koch WJ, Caron MG, Lefkowitz RJ. Inglese J, et al. Among authors: lefkowitz rj. Nature. 1992 Sep 10;359(6391):147-50. doi: 10.1038/359147a0. Nature. 1992. PMID: 1522899

3

Role of phosphorylation in desensitization of the beta-adrenoceptor.

Lefkowitz RJ, Hausdorff WP, Caron MG. Lefkowitz RJ, et al. Trends Pharmacol Sci. 1990 May;11(5):190-4. doi: 10.1016/0165-6147(90)90113-m. Trends Pharmacol Sci. 1990. PMID: 2188401 Review.

4

Removal of phosphorylation sites from the beta 2-adrenergic receptor delays onset of agonist-promoted desensitization.

Bouvier M, Hausdorff WP, De Blasi A, O'Dowd BF, Kobilka BK, Caron MG, Lefkowitz RJ. Bouvier M, et al. Among authors: lefkowitz rj. Nature. 1988 May 26;333(6171):370-3. doi: 10.1038/333370a0. Nature. 1988. PMID: 2836733

5

Switching of the coupling of the beta2-adrenergic receptor to different G proteins by protein kinase A.

Daaka Y, Luttrell LM, Lefkowitz RJ. Daaka Y, et al. Among authors: lefkowitz rj. Nature. 1997 Nov 6;390(6655):88-91. doi: 10.1038/36362. Nature. 1997. PMID: 9363896

6

Essential role for G protein-coupled receptor endocytosis in the activation of mitogen-activated protein kinase.

Daaka Y, Luttrell LM, Ahn S, Della Rocca GJ, Ferguson SS, Caron MG, Lefkowitz RJ. Daaka Y, et al. Among authors: lefkowitz rj. J Biol Chem. 1998 Jan 9;273(2):685-8. doi: 10.1074/jbc.273.2.685. J Biol Chem. 1998. PMID: 9422717 Free article.

7

Src-mediated tyrosine phosphorylation of dynamin is required for beta2-adrenergic receptor internalization and mitogen-activated protein kinase signaling.

Ahn S, Maudsley S, Luttrell LM, Lefkowitz RJ, Daaka Y. Ahn S, et al. Among authors: lefkowitz rj. J Biol Chem. 1999 Jan 15;274(3):1185-8. doi: 10.1074/jbc.274.3.1185. J Biol Chem. 1999. PMID: 9880482 Free article.

8

The beta(2)-adrenergic receptor mediates extracellular signal-regulated kinase activation via assembly of a multi-receptor complex with the epidermal growth factor receptor.

Maudsley S, Pierce KL, Zamah AM, Miller WE, Ahn S, Daaka Y, Lefkowitz RJ, Luttrell LM. Maudsley S, et al. Among authors: lefkowitz rj. J Biol Chem. 2000 Mar 31;275(13):9572-80. doi: 10.1074/jbc.275.13.9572. J Biol Chem. 2000. PMID: 10734107 Free article.

9

beta-arrestin1 interacts with the catalytic domain of the tyrosine kinase c-SRC. Role of beta-arrestin1-dependent targeting of c-SRC in receptor endocytosis.

Miller WE, Maudsley S, Ahn S, Khan KD, Luttrell LM, Lefkowitz RJ. Miller WE, et al. Among authors: lefkowitz rj. J Biol Chem. 2000 Apr 14;275(15):11312-9. doi: 10.1074/jbc.275.15.11312. J Biol Chem. 2000. PMID: 10753943 Free article.

10

Epidermal growth factor (EGF) receptor-dependent ERK activation by G protein-coupled receptors: a co-culture system for identifying intermediates upstream and downstream of heparin-binding EGF shedding.

Pierce KL, Tohgo A, Ahn S, Field ME, Luttrell LM, Lefkowitz RJ. Pierce KL, et al. Among authors: lefkowitz rj. J Biol Chem. 2001 Jun 22;276(25):23155-60. doi: 10.1074/jbc.M101303200. Epub 2001 Apr 4. J Biol Chem. 2001. PMID: 11290747 Free article.

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